7: Tight Binding Inhibition

Sep 3, 2016 by in GENERAL & FAMILY MEDICINE Comments Off on 7: Tight Binding Inhibition

approaches the total concentration of enzyme ([E]T) in the assay system. This situation is referred to as tight binding inhibition, and it presents some unique challenges for quantitative assessment of…

read more

1: Why Enzymes as Drug Targets?

Sep 3, 2016 by in GENERAL & FAMILY MEDICINE Comments Off on 1: Why Enzymes as Drug Targets?

Dehydrogenase Lovastatin and other statins HMG-CoA reductase Cholesterol lowering Methotrexate Dihydrofolate reductase Cancer, immunosuppression Nitecapone Catechol-O-methyltransferase Parkinson’s disease Norfloxacin DNA gyrase Urinary tract infections Omeprazole H+, K+ ATPase Peptic ulcers…

read more
Get Clinical Tree app for offline access