PATHOLOGY & LABORATORY MEDICINE

Testicular Germ Cell Tumors

Oct 14, 2017 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Testicular Germ Cell Tumors

Type Histologic spectrum Association with GCNIS Other anatomical sites Age of presentation Incidence (per 100,000) Originating cell Cytogenetic abnormality Ploidy I Prepubertal-type teratoma Dermoid cysts Possibly epidermoid cysts Prepubertal yolk…

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Germ Cell Tumors from a Developmental Perspective: Cells of Origin, Pathogenesis, and Molecular Biology (Emerging Patterns)

Oct 14, 2017 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Germ Cell Tumors from a Developmental Perspective: Cells of Origin, Pathogenesis, and Molecular Biology (Emerging Patterns)

Fig. 3.1 Cycle of genomic imprinting (GI). Upon fertilization, the zygote acquires a haploid set of paternally imprinted chromosomes from the father and a haploid set of maternally imprinted chromosomes…

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Central Nervous System Germ Cell Tumors

Oct 14, 2017 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Central Nervous System Germ Cell Tumors

Germinoma Embryonal carcinoma Yolk sac tumor Choriocarcinoma Teratoma  Immature  Mature  With malignant transformation Mixed germ cell Other proposed classification systems separate histologic variants into different therapeutic groups based on their…

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