Altered acinar cells are found with moderate frequency when multiple sections of pancreas are evaluated (Fig. 35.2). Acinar dilatation (acinar ectasia) is rare in surgical specimens (28) and has been…

The vast majority of testicular tumors are of germ cell origin and, like the totipotent germ cells from which they arise, may differentiate along several pathways. The distinction of seminoma…

MYOMECTOMY SPECIMENS Myomectomies are performed in women who wish to retain their uterus, usually to relieve symptoms produced by the neoplasm. Although there is no evidence to support this, myomectomies…

Simple radiographic localization of a mediastinal mass has considerable value in and of itself. Substantial information is available on the relative likelihood of any given lesion in the three anatomically…

When infections are excluded, lung biopsy specimens for diffuse infiltrative pulmonary disease are most likely to be from patients with idiopathic interstitial pulmonary fibrosis or sarcoidosis (1). Most other conditions,…

These residual odontogenic rests may be encountered in histologic evaluation of extracted teeth or in sections of tooth-bearing jaws. Odontogenic rests are typically round or strandlike in form (Fig. 19.2)….

The number of blocks submitted from specimens varies depending on circumstances. It is important, however, that tumors be sampled thoroughly because their microscopic appearance may vary from area to area….

Blood draining from the gastrointestinal (GI) tract flows through the portal veins and eventually into terminal portal venules and then sinusoids, where it mixes with arterial blood (which enters the…

TISSUE SAMPLING AND PREPARATION Renal tissue samples are usually obtained by percutaneous or open renal biopsy or by nephrectomy. The biopsy is divided for LM, IF, and EM. The specimen…

The mucosal layer is thrown into variably sized branching folds, which are more prominent when the organ is contracted. The surface epithelium consists of a single layer of tall columnar…