Tumor Markers
Chapter 24 Tumor Markers Lori J. Sokoll, Ph.D., F.A.C.B., Alex J. Rai, Ph.D., D.A.B.C.C., F.A.C.B. and Daniel W. Chan, Ph.D., D.A.B.C.C., F.A.C.B A tumor marker is a substance produced by…
Preanalytical Variables and Biological Variation
Chapter 6 Preanalytical Variables and Biological Variation Donald S. Young, M.B., Ph.D. The human body is composed of many different compounds and elements; the concentration or activity of these analytes…
Point-of-Care Testing
Chapter 20 Point-of-Care Testing Christopher P. Price, Ph.D., F.R.S.C., F.R.C.Path. and Andrew St. John, Ph.D., M.A.A.C.B. Advances in a range of analytical and fabrication technologies, such as (1) thin film…
Principles of Molecular Biology
Chapter 37 Principles of Molecular Biology Rossa W.K. Chiu, M.B.B.S., Ph.D., F.H.K.A.M.(Pathology), F.R.C.P.A. and Y.M. Dennis Lo, M.A., D.M., D.Phil., F.R.C.P.,(Lond. & Edin.), F.R.C.Path., F.R.S. Molecular diagnostics represents one of…
Molecular Methods in Diagnosis and Monitoring of Infectious Diseases
Chapter 42 Molecular Methods in Diagnosis and Monitoring of Infectious Diseases Aaron D. Bossler, M.D., Ph.D. and Angela M. Caliendo, M.D., Ph.D. In the short time since their introduction, nucleic…
Identity Assessment
Chapter 41 Identity Assessment Thomas M. Williams, M.D., Howard J. Baum, Ph.D., Victor W. Weedn, M.D., J.D. and Malek Kamoun, M.D., Ph.D. Identity testing exploits variations present within the human…
Clinical Utility of Laboratory Tests
Chapter 3 Clinical Utility of Laboratory Tests Edward R. Ashwood, M.D. and David E. Bruns, M.D.* A vast majority of medical decisions rely on laboratory testing. Clinicians often ask which…
Evidence-Based Laboratory Medicine
Chapter 4 Evidence-Based Laboratory Medicine Christopher P. Price, Ph.D., F.R.S.C., F.R.C.Path., Patrick M.M. Bossuyt, Ph.D. and David E. Bruns, M.D. This chapter expands upon the “Principles of Laboratory Medicine.” We…
Toxic Metals
Chapter 36 Toxic Metals Thomas P. Moyer, Ph.D. Metals have been recognized as toxins for centuries. For example, arsenic (As) poisoning was a favored way to dethrone royalty in the…
