Clinical Drug Evaluation and Regulatory Approval

Aug 3, 2016 by in PHARMACY Comments Off on Clinical Drug Evaluation and Regulatory Approval

FDA Review FDA Approval Approval in Other Countries Expanded Access of an Investigational Drug or an Approved Drug with Restricted Distribution Drug Labeling Drug Naming Additional Indications REGULATORY ASPECTS OF…

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General Anesthetic Pharmacology

Aug 3, 2016 by in PHARMACY Comments Off on General Anesthetic Pharmacology

   INTRODUCTION Before the discovery of general anesthetics, pain and shock severely limited the possibilities for surgical intervention. Postoperative mortality dropped dramatically following the first public demonstration of diethyl ether at…

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Pharmacokinetics

Aug 3, 2016 by in PHARMACY Comments Off on Pharmacokinetics

   INTRODUCTION Even the most promising of pharmacologic therapies will fail in clinical trials if the drug is unable to reach its target organ at a concentration sufficient to have a…

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Pharmacology of Hemostasis and Thrombosis

Aug 3, 2016 by in PHARMACY Comments Off on Pharmacology of Hemostasis and Thrombosis

   INTRODUCTION Blood carries oxygen and nutrients to tissues and takes metabolic waste products away from tissues. Humans have developed a well-regulated system of hemostasis to keep the blood fluid and…

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Pharmacology of Eicosanoids

Aug 3, 2016 by in PHARMACY Comments Off on Pharmacology of Eicosanoids

Pharmacology of Eicosanoids David M. Dudzinski and Charles N. Serhan INTRODUCTION & CASE PHYSIOLOGY OF EICOSANOID METABOLISM Generation of Arachidonic Acid and Omega-3 Fatty Acids Cyclooxygenase Pathway Prostaglandins Thromboxane and…

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Pharmacology of Viral Infections

Aug 3, 2016 by in PHARMACY Comments Off on Pharmacology of Viral Infections

Pharmacology of Viral Infections Jonathan Z. Li and Donald M. Coen INTRODUCTION & CASE PHYSIOLOGY OF VIRAL REPLICATION Viral Life Cycle PHARMACOLOGIC CLASSES AND AGENTS Inhibition of Viral Attachment and…

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Pharmacology of Cardiac Rhythm

Aug 3, 2016 by in PHARMACY Comments Off on Pharmacology of Cardiac Rhythm

   INTRODUCTION The human heart is both a mechanical and an electrical organ. To perfuse the body adequately with blood, the mechanical and electrical components of the heart must work in…

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