of Developmental Mechanisms in Embryogenesis
Figure 14-23 This scanning electron micrograph of a 4-week human embryo illustrates the early budding of the forelimb. Overlaid onto the bud are the three axes of limb specification: Do-V, dorsal-ventral (dorsal…
Variation and Polymorphism in DNA
bp, Base pair; kb, kilobase pair; Mb, megabase pair. Figure 4-1 Three polymorphisms in genomic DNA from the segment of the human genome reference assembly shown at the top (see also…
Case Studies Illustrating Genetic Principles
Case 1. Abacavir-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (Genetically Determined Immunological Adverse Drug Reaction)
Human Genome and the Chromosomal Basis of Heredity
Figure 2-1 The human genome, encoded on both nuclear and mitochondrial chromosomes. See Sources & Acknowledgments. In addition to the nuclear genome, a small but important part of the human genome…
for Specific Topics
References for Specific Topics Biesecker LG. Incidental variants are critical for genomics. Am J Hum Genet. 2013;92:648–651. Elger B, Michaud K, Mangin P. When information can save lives: the duty…
References
General References Beauchamp TL, Childress JF. Principles of biomedical ethics. ed 5. Oxford University Press: New York; 2001. Kevles D. In the name of eugenics: genetics and the uses of…
of Genetic Information
A woman first presents with an autosomal dominant disorder at the age of 40 years, undergoes testing, and is found to carry a particular mutation in a gene known to…
