Sclerotic Fibroma
Typically does not show prominent storiforming of collagen, although it may be focally present in rare cases • Pleomorphic fibroma Pleomorphic cells are more prominent, and storiforming pattern of collagen should…
Acral Fibrokeratoma
More cellular than acral fibrokeratoma Fascicles of spindled cells Lacks vertically oriented collagen bundles CD34(+) • Superficial acral fibromyxoma More cellular lesion Loose storiform to fascicular growth pattern Lacks vertically oriented…
Pilar Sheath Acanthoma
Pilar Sheath AcanthomaScanning magnification of a pilar sheath acanthoma shows a dilated follicular structure lined by a thickened squamous epithelium with endophytic, lobulated areas . Pilar Sheath Acanthoma at Higher…
Superficial Acral Fibromyxoma
Particularly in or near nail bed • Solitary, slowly growing, and often long-standing lesion • Treatment: Complete excision • Excellent prognosis • Low rate of recurrence, usually related to incomplete excision Macroscopic • Usually <…
Angiolymphoid Hyperplasia With Eosinophilia
Endothelial cells may have cytoplasmic vacuolization May have solid appearance • Many eosinophils, lymphocytes, and mast cells, although eosinophil number can vary greatly Top Differential Diagnoses • Papillary endothelial hyperplasia • Kimura disease…
Staging for Specimens of Squamous Cell Carcinoma of Skin
pN2a: Metastasis in single ipsilateral lymph node, > 3 cm to < 6 cm in greatest dimension pN2b: Metastasis in multiple ipsilateral lymph nodes, none > 6 cm in greatest…
Progressive Lymphangioma
Presents in infants or young children as multiple small vesicular lesions • Lymphangiomatosis Diffuse involvement of multiple organ systems, including skin, soft tissues, bone, and internal organs • Atypical vascular lesion (radiotherapy-related)…
Spindle Cell Hemangioma
Spindle Cell HemangiomaLow magnification shows a noncircumscribed lesion in the dermis and subcutis composed of an admixture of thin-walled dilated blood vessels and sheets of spindle cells. Spindle Cell Hemangioma…
Glomeruloid Hemangioma
Glomeruloid Hemangioma at Scanning MagnificationScanning magnification view of a glomeruloid hemangioma shows small clusters of vessels in the mid to deep dermis . Glomeruloid Hemangioma at Higher MagnificationHigher magnification shows…
Steatocystoma (Multiplex)
Has granular layer, rather than eosinophilic cuticle of steatocystoma Lacks associated sebaceous glands • Dermoid cyst Occurs in younger patients Has granular layer, rather than eosinophilic cuticle of steatocystoma • Epidermoid cyst/epidermal…
