Glomeruloid Hemangioma


Glomeruloid Hemangioma at Scanning Magnification
Scanning magnification view of a glomeruloid hemangioma shows small clusters of vessels in the mid to deep dermis image.



image
Glomeruloid Hemangioma at Higher Magnification
Higher magnification shows the grape-like pattern of clustered small vessels, mimicking renal glomeruli.

image
Glomeruloid Hemangioma With Grape-Like Vascular Clusters
High-power view of a glomeruloid hemangioma shows small, grape-like clusters of vessels projecting into vascular lumina (with peripheral crescentic spaces image present).

image
Glomeruloid Hemangioma at High Magnification
High magnification of the vessels in a glomeruloid hemangioma shows endothelial cells with oval to spindle-shaped nuclei. Cytoplasmic eosinophilic globules are present focally image. A few intraluminal eosinophils are also present image.


TERMINOLOGY


Abbreviations




• Glomeruloid hemangioma


Synonyms




• Glomeruloid angioma


Definitions




• Benign proliferation of small vessels mimicking renal glomeruli


ETIOLOGY/PATHOGENESIS


Paraneoplastic Syndrome




• Association with polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes (POEMS) syndrome or multicentric Castleman disease in most cases


Unknown




• Rare cases not associated with POEMS syndrome


CLINICAL ISSUES


Epidemiology




• Incidence
image Rare tumors

• Sex
image More common in females

• Ethnicity
image More common in Asians (Japanese)

Apr 24, 2017 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Glomeruloid Hemangioma

Full access? Get Clinical Tree

Get Clinical Tree app for offline access