Glomeruloid Hemangioma at Scanning Magnification Scanning magnification view of a glomeruloid hemangioma shows small clusters of vessels in the mid to deep dermis .
Glomeruloid Hemangioma at Higher Magnification Higher magnification shows the grape-like pattern of clustered small vessels, mimicking renal glomeruli.
Glomeruloid Hemangioma With Grape-Like Vascular Clusters High-power view of a glomeruloid hemangioma shows small, grape-like clusters of vessels projecting into vascular lumina (with peripheral crescentic spaces present).
Glomeruloid Hemangioma at High Magnification High magnification of the vessels in a glomeruloid hemangioma shows endothelial cells with oval to spindle-shaped nuclei. Cytoplasmic eosinophilic globules are present focally . A few intraluminal eosinophils are also present .
TERMINOLOGY
Abbreviations
• Glomeruloid hemangioma
Synonyms
• Glomeruloid angioma
Definitions
• Benign proliferation of small vessels mimicking renal glomeruli
ETIOLOGY/PATHOGENESIS
Paraneoplastic Syndrome
• Association with polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes (POEMS) syndrome or multicentric Castleman disease in most cases
Unknown
• Rare cases not associated with POEMS syndrome
CLINICAL ISSUES
Epidemiology
• Incidence
Rare tumors
• Sex
More common in females
• Ethnicity
More common in Asians (Japanese)
Site
• Trunk and extremities
Only gold members can continue reading. Log In or Register to continue