Multinucleate Cell Angiohistiocytoma



Multinucleate Cell Angiohistiocytoma


David Cassarino, MD, PhD










Low-power examination of multinucleate cell angiohistiocytoma shows a dermal-based proliferation of small vessels with focal telangiectasia and increased numbers of stromal cells.






Higher power view shows a proliferation of numerous small blood vessels and scattered enlarged, angulated mononuclear and multinucleated image stromal cells.


TERMINOLOGY


Abbreviations



  • Multinucleate cell angiohistiocytoma (MCAH)


Definitions



  • Proliferation of vessels and multinucleated stromal cells


ETIOLOGY/PATHOGENESIS


Unknown



  • May actually represent a nonneoplastic reactive process


  • Some authors consider MCAH a variant of dermatofibroma


CLINICAL ISSUES


Epidemiology



  • Age



    • Usually presents in patients > 40 years old


  • Gender



    • Typically occurs in females

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Multinucleate Cell Angiohistiocytoma

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