Spindle Cell Hemangioma Low magnification shows a noncircumscribed lesion in the dermis and subcutis composed of an admixture of thin-walled dilated blood vessels and sheets of spindle cells.
Spindle Cell Hemangioma Arising Within Vessel Low magnification of a spindle cell hemangioma shows a well-circumscribed intravascular tumor with ectatic vascular spaces and a cellular spindle cell proliferation. There is a remnant of a preexisting vessel at the periphery .
Spindle Cells in Spindle Cell Hemangioma High magnification of spindle cell hemangioma shows straight/curved fascicles of uniform spindle cells with irregularly shaped vascular spaces and small areas of hemorrhage.
High-Power Image of Spindle Cell Hemangioma High magnification shows the spindled tumor cells and the characteristic vacuolated endothelial cells (so-called blister cells).
TERMINOLOGY
Synonyms
• Formerly known as spindle cell hemangioendothelioma
Definitions
• Benign vascular tumor characterized by cavernous vascular spaces and spindled cell areas
ETIOLOGY/PATHOGENESIS
Unknown
• Some cases associated with Maffucci syndrome, Klippel-Trenaunay syndrome, varicosities, and congenital lymphedema
CLINICAL ISSUES
Epidemiology
• Age
Young adults
Site
• Distal extremities
Acral location most common
Presentation
• Subcutaneous mass
Sometimes multifocal
Treatment
• Surgical approaches
Excision
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