Spindle Cell Hemangioma


Spindle Cell Hemangioma
Low magnification shows a noncircumscribed lesion in the dermis and subcutis composed of an admixture of thin-walled dilated blood vessels and sheets of spindle cells.



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Spindle Cell Hemangioma Arising Within Vessel
Low magnification of a spindle cell hemangioma shows a well-circumscribed intravascular tumor with ectatic vascular spaces image and a cellular spindle cell proliferation. There is a remnant of a preexisting vessel at the periphery image.

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Spindle Cells in Spindle Cell Hemangioma
High magnification of spindle cell hemangioma shows straight/curved fascicles of uniform spindle cells image with irregularly shaped vascular spaces image and small areas of hemorrhage.

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High-Power Image of Spindle Cell Hemangioma
High magnification shows the spindled tumor cells and the characteristic vacuolated endothelial cells (so-called blister cells).


TERMINOLOGY


Synonyms




• Formerly known as spindle cell hemangioendothelioma


Definitions




• Benign vascular tumor characterized by cavernous vascular spaces and spindled cell areas


ETIOLOGY/PATHOGENESIS


Unknown




• Some cases associated with Maffucci syndrome, Klippel-Trenaunay syndrome, varicosities, and congenital lymphedema


CLINICAL ISSUES


Epidemiology




• Age
image Young adults


Site




• Distal extremities
image Acral location most common


Presentation




• Subcutaneous mass
image Sometimes multifocal

Apr 24, 2017 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Spindle Cell Hemangioma
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