Has granular layer, rather than eosinophilic cuticle of steatocystoma
Lacks associated sebaceous glands
• Dermoid cyst
Occurs in younger patients
Has granular layer, rather than eosinophilic cuticle of steatocystoma
• Epidermoid cyst/epidermal inclusion cyst
Has granular layer
Lacks sebaceous glands in cyst wall
• Pilar cyst
Exhibits abrupt trichilemmal keratinization
Lack sebaceous glands
Steatocystoma With Multiple Thin-Walled Cystic Spaces Steatocystomas present as thin-walled dermal cysts. Note the normal epidermis in the upper left corner and sebaceous glands in the cyst wall .
Typical Steatocystoma With Sebaceous Glands The cyst is lined by a thin squamous epithelial lining that has an eosinophilic cuticle and is associated with sebaceous glands .
High Magnification of Lining of Steatocystoma The key diagnostic feature is the eosinophilic cuticle lining the cyst wall. It has an undulating crenulated appearance.
High Magnification of Steatocystoma With Vellus Hair Shaft The eosinophilic cuticle with its undulating, crenulated appearance is a key diagnostic feature. This cyst also has a fragment of a vellus hair shaft , a feature sometimes seen in steatocystomas.
TERMINOLOGY
Definitions
• Benign cyst derived from sebaceous duct that may present as multiple lesions (steatocystoma multiplex) or as single lesion (steatocystoma simplex)
CLINICAL ISSUES
Epidemiology
• Incidence
Uncommon
• Age
Steatocystoma multiplex usually presents in adolescents
Steatocystoma simplex usually presents in adults
Site
• May occur at any site, but trunk is most common location for steatocystoma multiplex
Axillae and groin commonly affected in female patients
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