Pharmaceutical nanotechnology

Aug 14, 2016 by in PHARMACY Comments Off on Pharmaceutical nanotechnology

Figure 14.1 Nanosystems that exist in nature (not to scale). Left to right: an insulin hexamer (3.5 × 5 nm), a low-density lipoprotein (LDL) particle (28 nm) and a parvovirus (20–25 nm). LDL…

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Solids

Aug 14, 2016 by in PHARMACY Comments Off on Solids

Figure 1.1 Classification of solids. 1.2 Crystalline solids: structure and properties 1.2.1 Crystal structure Crystals contain highly ordered arrays of molecules and atoms held together by non-covalent interactions. We can consider as a…

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Paediatric and geriatric formulations

Aug 14, 2016 by in PHARMACY Comments Off on Paediatric and geriatric formulations

Figure 10.1 The matrix of drivers for special formulations. 10.2 Paediatric medication Children are far from being a homogeneous group. They range from: preterm newborn infants (premature: average weight <3.4 kg) full-term…

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Generic medicines and biosimilars

Aug 14, 2016 by in PHARMACY Comments Off on Generic medicines and biosimilars

Key point The search for true bioequivalence is important. Given the variability of human drug response, to which we have referred several times, it is even more important that the product…

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Physical assessment of dosage forms

Aug 14, 2016 by in PHARMACY Comments Off on Physical assessment of dosage forms

15 Physical assessment of dosage forms It is important to have means of studying the key characteristics of quality of formulations during development and for quality control purposes during production…

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Surfactants

Aug 14, 2016 by in PHARMACY Comments Off on Surfactants

5 Surfactants Certain compounds, because of their chemical structure, have a tendency to accumulate at the boundary between two phases. Such compounds are termed amphiphiles, surface-active agents or surfactants. Their…

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