HIV-associated Collapsing Glomerulopathy
HIV-associated Collapsing Glomerulopathy A. Brad Farris, III, MD Key Facts Clinical Issues Up to 90% of cases occur in African-American blacks, mostly male Rapid progression to ESRD Hypertension uncommon (in…
Hepatitis C Virus
Hepatitis C Virus Anthony Chang, MD Key Facts Terminology Hepatitis C virus (HCV) Wide spectrum of immune complex-mediated glomerular injuries in association with HCV infection Clinical Issues Over 200 million…
Obstructive Nephropathy
Obstructive Nephropathy Sanjay Jain, MD, PhD Helen Liapis, MD Key Facts Terminology Acute or chronic damage to kidney due to obstruction of urine flow Etiology/Pathogenesis Many causes, congenital and acquired…
Nephrolithiasis
Nephrolithiasis Shane M. Meehan, MBBCh Key Facts Terminology Concretion of urinary mineral or inorganic crystals in kidney Etiology/Pathogenesis Causes 25% known cause 50% idiopathic hypercalciuria 25% unknown cause Clinical Issues…
Reflux Nephropathy
Reflux Nephropathy Sanjay Jain, MD, PhD Helen Liapis, MD Key Facts Terminology Reflux nephropathy: Renal parenchymal scarring due to urine reflux Etiology/Pathogenesis Vesicoureteral reflux (VUR), UTIs Exposure of kidneys to…
Amyloidosis
Amyloidosis A. Brad Farris, III, MD Key Facts Terminology Accumulation of any 1 of > 20 amyloid proteins, characterized by apple-green birefringence after Congo red stain due to β-pleated sheet…
Collapsing Glomerulopathy
Collapsing Glomerulopathy A. Brad Farris, III, MD Key Facts Etiology/Pathogenesis Podocyte proliferation and dedifferentiation are thought to play a role Idiopathic most common form Heterogeneous secondary forms Infection: HIV, parvovirus…
Renal Artery Stenosis
Renal Artery Stenosis A. Brad Farris, III, MD Key Facts Etiology/Pathogenesis Renal artery stenosis from variety of potential causes results in ischemic atrophy Atherosclerosis with atheromatous plaques is one of…
Hypertensive Renovascular Disease
Hypertensive Renovascular Disease A. Brad Farris, III, MD Key Facts Terminology Vascular and glomerular disease 2° to hypertension Clinical Issues ˜ 30% of American adults have hypertension 95% due to…
Drug-induced Acute Interstitial Nephritis
Drug-induced Acute Interstitial Nephritis Neeraja Kambham, MD Key Facts Terminology Acute tubulointerstitial inflammation due to allergic reaction to a drug Etiology/Pathogenesis T-cell-mediated hypersensitivity reaction Idiosyncratic reaction, not dose dependent Clinical…
