Iatrogenic Changes
Iatrogenic Changes Key Facts Etiology/Pathogenesis Pathologic changes occur in breast due to prior surgery, radiation therapy, and medical treatment Treatment-related changes are important to recognize Clinical Issues Excisions after core…
Fibroadenoma
Fibroadenoma Key Facts Terminology Fibroadenoma (FA) Most common benign solid breast neoplasm Well-circumscribed lesion Proliferation of epithelial and stromal elements Etiology/Pathogenesis FAs are due to proliferation of lobular stroma and…
Phyllodes Tumor
Phyllodes Tumor Key Facts Terminology Derived from the Greek word “phyllos” meaning “leaf” Biphasic tumor consisting of epithelial-lined clefts separating areas of cellular stroma, creating leaf-like fronds Clinical Issues Uncommon:…
Ductal Carcinoma In Situ
Ductal Carcinoma In Situ Key Facts Etiology/Pathogenesis Same molecular subtypes recognized in invasive carcinoma are also seen in DCIS Transition to invasion is poorly understood May involve loss of function…
Squamous Metaplasia of Lactiferous Ducts
Squamous Metaplasia of Lactiferous Ducts Key Facts Terminology Squamous metaplasia of lactiferous ducts (SMOLD) is also known as recurrent subareolar abscess, periductal mastitis, and Zuska disease Etiology/Pathogenesis Keratin-producing cells extend…
Ductal Carcinoma In Situ, Paget Disease
Ductal Carcinoma In Situ, Paget Disease Key Facts Terminology Mammary Paget disease (MPD) Uncommon clinical presentation of breast cancer involving nipple Clinical Issues Occurs in 1-2% of women with breast…
Lymph Node Metastases
Lymph Node Metastases Radioactive tracer or blue dye can be used to identify the sentinel node, which is the node (or often 2 nodes) that first receives lymphatic drainage from…
Lymph-Vascular Invasion
Lymph-Vascular Invasion LVI is the presence of tumor emboli within lymphatic spaces that are typically associated with small arterioles and veins . The presence of LVI is associated with lymph…
