Giant Cell Tumor
Giant Cell Tumor G. Petur Nielsen, MD Andrew E. Rosenberg, MD Key Facts Terminology Neoplasm composed of cytologically benign, oval or polyhedral mononuclear cells that are admixed with numerous, evenly…
Aneurysmal Bone Cyst
Aneurysmal Bone Cyst G. Petur Nielsen, MD Andrew E. Rosenberg, MD Key Facts Terminology Destructive, expansile benign neoplasm of bone characterized by multiloculated blood-filled cystic spaces Classified into primary and…
Ewing Sarcoma/Primitive Neuroectodermal Tumor (Pnet)
Ewing Sarcoma/Primitive Neuroectodermal Tumor (Pnet) G. Petur Nielsen, MD Andrew E. Rosenberg, MD Key Facts Terminology Malignant small round cell sarcoma showing variable degree of neuroectodermal differentiation Clinical Issues Accounts…
Primary Lymphoma
Primary Lymphoma G. Petur Nielsen, MD Andrew E. Rosenberg, MD Key Facts Terminology Primary lymphoma of bone is defined as lymphoma originating in bone ± extension into adjacent soft tissues…
Plasmacytoma/Myeloma
Plasmacytoma/Myeloma Vikram Deshpande, MD G. Petur Nielsen, MD Andrew E. Rosenberg, MD Key Facts Terminology Plasma cell myeloma is a bone-marrow-based, multifocal plasma cell neoplasm associated with M protein in…
Adipocytic Tumors
Adipocytic Tumors G. Petur Nielsen, MD Andrew E. Rosenberg, MD Key Facts Terminology Liposarcoma Extremely rare malignant neoplasm with a phenotype that recapitulates fat Lipoma Benign neoplasm of mature adipocytes…
Molecular Factors Index
Molecular Factors Index Molecular Factors Discussed Molecular Factor Chromosomal Location Definition/Alternative Names Chapters 12q13-15 Fibrous Dysplasia 16q22 Aneurysmal Bone Cyst 1p Ewing Sarcoma/Primitive Neuroectodermal Tumor (PNET) 4p16.3 Giant Cell Reparative…
Antibody Index
Antibody Index Antibodies Discussed Antibody Name/Symbol Antibody Description Clones/Alternative Names Chapters β-2-microglobulin component of MHC class I molecules B2-MICROGLB Amyloidoma β-catenin beta catenin; involved in regulation of cell adhesion and…
Protocol For Examination Of Bone Tumor Specimens
Protocol For Examination Of Bone Tumor Specimens G. Petur Nielsen, MD Andrew E. Rosenberg, MD Bone: Biopsy Surgical Pathology Cancer Case Summary (Checklist) Specimen Specify bone involved (if known): ______________________________…
Enchondroma
Enchondroma G. Petur Nielsen, MD Andrew E. Rosenberg, MD Key Facts Terminology Common benign primary bone tumor that accounts for approximately 3-10% of all bone tumors Clinical Issues Usually presents…
