Splenic Inflammatory Pseudotumor Roberto N. Miranda, MD Key Facts Terminology Splenic inflammatory pseudotumor (IPT) Clinical Issues Age: 19-87 years (median: 53 years) Rare in children Slight female predominance Excision is…
Primary Cutaneous Follicle Center Lymphoma Roberto N. Miranda, MD Key Facts Terminology Lymphoma arising in skin composed of follicular center cells Subset of cases appear to be clinically and genetically…
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Roberto N. Miranda, MD Key Facts Terminology CLL/SLL is neoplasm of small B lymphocytes that typically involves peripheral blood (PB), bone marrow (BM), lymph nodes,…
Nodal Follicular Lymphoma C. Cameron Yin, MD, PhD Key Facts Terminology B-cell neoplasm composed of germinal center B cells (centrocytes and centroblasts) Etiology/Pathogenesis Overexpression of antiapoptotic Bcl-2 due to t(14;18)…
Splenic Diffuse Red Pulp Small B-cell Lymphoma Roberto N. Miranda, MD Key Facts Terminology Abbreviation: SDRP SBCL Provisional entity in 2008 WHO classification Clinical Issues Low level of lymphocytosis Splenomegaly;…
Inflammatory Pseudotumor-like Follicular Dendritic Cell Tumor Roberto N. Miranda, MD Key Facts Terminology Inflammatory pseudotumor-like follicular dendritic cell tumor (IPT-FDCT) Considered variant of follicular dendritic cell sarcoma Classification is controversial…
Post-Chemotherapy Histiocyte-rich Pseudotumor of Spleen Roberto N. Miranda, MD Key Facts Terminology Residual splenic mass after chemotherapy composed of viable nonneoplastic cells and necrotic neoplastic cells Etiology/Pathogenesis Chemotherapy is toxic…
Lymphomatoid Granulomatosis Francisco Vega, MD, PhD Key Facts Terminology Extranodal angiocentric &/or angiodestructive EBV(+) B-cell lymphoproliferative disorder Clinical Issues Most frequent in young adults (˜ 30-40 years) Lung is most…
Mycosis Fungoides Sa A. Wang, MD Key Facts Terminology Primary cutaneous T-cell lymphoma characterized by Epidermotropism Clinical course showing stepwise evolution of patches, plaques, and tumors Clinical Issues Overall indolent…
Autoimmune Lymphoproliferative Syndrome Sa A. Wang, MD Key Facts Etiology/Pathogenesis Disease of disrupted lymphocyte homeostasis as result of defective Fas-mediated apoptosis Many mutations have been identified in ALPS Type I:…
