Pseudoxanthoma Elasticum Irina Margaritescu, MD, DipRCPath Key Facts Terminology Inherited disorder characterized by fragmentation and progressive calcification of elastic tissue in dermis, blood vessels, and Bruch membrane of eye Microscopic…
Nephrogenic Fibrosing Dermopathy (Nephrogenic Systemic Fibrosis) Cary Chisholm, MD Key Facts Etiology/Pathogenesis Gadolinium administration prior to magnetic resonance (MR) imaging Clinical Issues History of renal failure is universally present Dialysis…
Granulomatosis with Polyangiitis Brian J. Hall, MD Key Facts Clinical Issues Correlation of clinical and histologic (most commonly LCV) findings with ANCA serology (most often PR3/c-ANCA positivity) can allow for…
Degos Disease Brian J. Hall, MD Bruce R. Smoller, MD Key Facts Terminology Idiopathic, rare thrombotic disorder characterized by distinctive skin lesions, often associated with infarctive lesions of other organs…
Traumatic Panniculitis Carly A. Elston Dirk Elston, MD Key Facts Terminology Localized organizing necrosis of subcutaneous fat resulting from physical or chemical injury Clinical Issues Commonly presents as breast mass…
Pityriasis Lichenoides Julie E. Jackson, MD Chandra N. Smart, MD Key Facts Terminology PLEVA Mucha-Habermann disease, febrile ulceronecrotic Mucha-Habermann disease Recurrent crops of erythematous papules of unknown etiology favoring children…
Lipodermatosclerosis Wang L. Cheung, MD, PhD Key Facts Terminology Sclerosing panniculitis, membranous lipodystrophy, sclerodermiform hypodermitis Clinical Issues Acute phase: Extremely painful, violaceous plaques in lower legs Chronic phase: Hyperpigmented induration…
Behçet Disease Brian J. Hall, MD Bruce R. Smoller, MD David J. DiCaudo, MD Key Facts Microscopic Pathology Diagnosis is primarily clinical Oral and genital lesions often show nonspecific ulceration…
Polyarteritis Nodosa Wang L. Cheung, MD, PhD Key Facts Terminology Vasculitis of medium- and small-sized blood vessels Clinical Issues Livedo reticularis with ulcers Painful nodules in lower extremities Systemic symptoms:…
Transient Neonatal Pustular Melanosis Larissa V. Furtado, MD Key Facts Clinical Issues Benign, self-limited dermatosis Most commonly occur in African-American infants (˜ 4-5%) No gender predilection Lesions are apparent at…
