Basicmedical Key

Chapter 4 Evidence-Based Laboratory Medicine Christopher P. Price, Ph.D., F.R.S.C., F.R.C.Path., Patrick M.M. Bossuyt, Ph.D. and David E. Bruns, M.D. This chapter expands upon the “Principles of Laboratory Medicine.” We…

Chapter 36 Toxic Metals Thomas P. Moyer, Ph.D. Metals have been recognized as toxins for centuries. For example, arsenic (As) poisoning was a favored way to dethrone royalty in the…

Chapter 7 Specimen Collection and Processing Doris M. Haverstick, Ph.D., D.A.B.C.C. and Amy R. Groszbach, M.E.D., M.L.T., M.B.(A.S.C.P.)C.M.* Proper collection, identification, processing, storage, and transport of common sample types associated…

Chapter 38 Genomes and Nucleic Acid Alterations Carl T. Wittwer, M.D., Ph.D. and Noriko Kusukawa, Ph.D. Molecular diagnostics focuses on medically important sequence variations within a background of complex genomic…

Chapter 45 Plasma Nucleic Acids Y.M. Dennis Lo, M.A., D.M., D.Phil., F.R.C.P.(Lond. & Edin.), F.R.C.Path., F.R.S., and Rossa W.K. Chiu, M.B.B.S., Ph.D., F.H.K.A.M.(Pathology), F.R.C.P.A. With the notable exception of virology,…

Chapter 23 Enzymes of the Red Blood Cell Wouter W. van Solinge, Ph.D. and Richard van Wijk, Ph.D. Erythrocytes perform a variety of functions, the most important being the binding,…

Chapter 39 Nucleic Acid Isolation Rossa W.K. Chiu, M.B.B.S., Ph.D., F.H.K.A.M.(Pathology), F.R.C.P.A. and Y.M. Dennis Lo, M.A., D.M., D.Phil., F.R.C.P.,(Lond. & Edin.), F.R.C.Path., F.R.S.* Many of the key advances in…

Chapter 19 Automation in the Clinical Laboratory James C. Boyd, M.D. and Charles D. Hawker, Ph.D., M.B.A., F.A.C.B. The term automation has been applied in clinical chemistry to describe the…