CHAPTER 30 Abnormalities in immunoglobulin synthesizing cells FE. Davies, KC. Anderson Chapter contents MULTIPLE MYELOMA 452 Epidemiology and etiology 452 Biology 452 The cell of origin 452 Biology and growth…
CHAPTER 27 Myelodysplastic/myeloproliferative neoplasms M. Czader, A. Orazi Chapter contents INTRODUCTION 391 CHRONIC MYELOMONOCYTIC LEUKEMIA 392 Definition and diagnostic criteria 392 Epidemiology, clinical and laboratory features 392 Morphology and immunophenotypic…
CHAPTER 33 Acquired disorders affecting megakaryocytes and platelets D. Provan, AC. Newland, PK. MacCallum Chapter contents INTRODUCTION 523 STRUCTURE AND FUNCTION OF MEGAKARYOCYTES AND PLATELETS 524 Human platelets 524 Platelet…
CHAPTER 23 Essential thrombocythemia and primary myelofibrosis HM. Kvasnicka Chapter contents INTRODUCTION 347 ESSENTIAL THROMBOCYTHEMIA (ET) 348 Clinical features 349 Molecular data 349 Blood and bone marrow findings 349 PRIMARY…
CHAPTER 20 Myelodysplastic syndromes BS. Wilkins, A. Porwit Chapter Contents DEFINITION 303 EPIDEMIOLOGY 303 CLASSIFICATION 304 DIAGNOSIS 304 BLOOD-FILM EXAMINATION 306 Erythrocytes 306 Leukocytes 307 Platelets 308 BONE MARROW EXAMINATION…
CHAPTER 28 The chronic lymphoid leukemias R. Rosenquist, A. Porwit Chapter contents CHRONIC LYMPHOCYTIC LEUKEMIA 407 Clinical features 407 Pathologic features 408 Peripheral blood 408 Bone marrow 408 Other tissues…
CHAPTER 18 Acute myeloid leukemias SD. Boyd, DA. Arber Chapter Contents INTRODUCTION 273 CLASSIFICATION SYSTEMS 274 Methods for diagnosis and classification 274 Clinical history 274 Peripheral blood and bone marrow…
CHAPTER 1 Normal blood cells SN. Wickramasinghe, WN. Erber Chapter contents ERYTHROCYTES 3 Morphology 3 Red cell parameters 3 Red cell life span 4 Functions of red cells 5 Reticulocytes…
CHAPTER 25 Myeloproliferative neoplasms with eosinophilia BJ. Bain Chapter contents MYELOID AND LYMPHOID NEOPLASMS WITH PDGFRA REARRANGEMENT 371 Clinical features 372 Pathologic features 372 Peripheral blood 372 Bone marrow 373…
CHAPTER 8 Erythroenzyme disorders DM. Layton, DR. Roper Chapter contents INTRODUCTION 121 CLINICAL FEATURES 121 BLOOD CELL MORPHOLOGY 122 BIOCHEMICAL INVESTIGATION OF ERYTHROENZYME DISORDERS 126 MOLECULAR BASIS OF ERYTHROENZYME DISORDERS…
