Histocompatibility: HLA and other systems
CHAPTER 39 Histocompatibility HLA and other systems PE. Posch, CK. Hurley Chapter contents INTRODUCTION 641 THE HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX 642 History 642 Genomic organization 642 THE HUMAN LEUKOCYTE ANTIGENS…
Abnormalities in immunoglobulin synthesizing cells
CHAPTER 30 Abnormalities in immunoglobulin synthesizing cells FE. Davies, KC. Anderson Chapter contents MULTIPLE MYELOMA 452 Epidemiology and etiology 452 Biology 452 The cell of origin 452 Biology and growth…
Myelodysplastic/myeloproliferative neoplasms
CHAPTER 27 Myelodysplastic/myeloproliferative neoplasms M. Czader, A. Orazi Chapter contents INTRODUCTION 391 CHRONIC MYELOMONOCYTIC LEUKEMIA 392 Definition and diagnostic criteria 392 Epidemiology, clinical and laboratory features 392 Morphology and immunophenotypic…
Acquired disorders affecting megakaryocytes and platelets
CHAPTER 33 Acquired disorders affecting megakaryocytes and platelets D. Provan, AC. Newland, PK. MacCallum Chapter contents INTRODUCTION 523 STRUCTURE AND FUNCTION OF MEGAKARYOCYTES AND PLATELETS 524 Human platelets 524 Platelet…
Essential thrombocythemia and primary myelofibrosis
CHAPTER 23 Essential thrombocythemia and primary myelofibrosis HM. Kvasnicka Chapter contents INTRODUCTION 347 ESSENTIAL THROMBOCYTHEMIA (ET) 348 Clinical features 349 Molecular data 349 Blood and bone marrow findings 349 PRIMARY…
Myelodysplastic syndromes
CHAPTER 20 Myelodysplastic syndromes BS. Wilkins, A. Porwit Chapter Contents DEFINITION 303 EPIDEMIOLOGY 303 CLASSIFICATION 304 DIAGNOSIS 304 BLOOD-FILM EXAMINATION 306 Erythrocytes 306 Leukocytes 307 Platelets 308 BONE MARROW EXAMINATION…
The chronic lymphoid leukemias
CHAPTER 28 The chronic lymphoid leukemias R. Rosenquist, A. Porwit Chapter contents CHRONIC LYMPHOCYTIC LEUKEMIA 407 Clinical features 407 Pathologic features 408 Peripheral blood 408 Bone marrow 408 Other tissues…
Acute myeloid leukemias
CHAPTER 18 Acute myeloid leukemias SD. Boyd, DA. Arber Chapter Contents INTRODUCTION 273 CLASSIFICATION SYSTEMS 274 Methods for diagnosis and classification 274 Clinical history 274 Peripheral blood and bone marrow…
Normal blood cells
CHAPTER 1 Normal blood cells SN. Wickramasinghe, WN. Erber Chapter contents ERYTHROCYTES 3 Morphology 3 Red cell parameters 3 Red cell life span 4 Functions of red cells 5 Reticulocytes…
