Anti-viral Drugs
26.1 INTRODUCTION TO ANTI-VIRAL DRUGS In this chapter we discuss another major application of virology: the development and use of drugs to combat virus diseases in humans. Drugs are available…
Parvoviruses (and Other ssDNA Viruses)
12.1 INTRODUCTION TO PARVOVIRUSES Parvoviruses are among the smallest known viruses, with virions in the range 18–26 nm in diameter. They derive their name from the Latin parvus (small). The…
Influenza Virus
16.1 INTRODUCTION TO INFLUENZA VIRUSES We are devoting a chapter to the influenza viruses because they are responsible for a huge disease burden and for hundreds of thousands of deaths…
Viruses and Cancer
23.1 INTRODUCTION TO VIRUSES AND CANCER A cancer in a human or an animal is a malignant tumor and involves continuous proliferation of a clone of cells derived from one…
Survival of Infectivity
24.1 PRESERVATION OF VIRUS INFECTIVITY There are several practical situations in which there is a need to preserve virus infectivity. A prime example is during the storage and distribution of…
Reoviruses (and Other dsRNA Viruses)
13.1 INTRODUCTION TO REOVIRUSES Icosahedral viruses with segmented genomes of dsRNA, isolated from the respiratory tracts and enteric tracts of humans and animals, and with which no disease could be…
Virus Genome Replication
7.1 OVERVIEW OF VIRUS GENOME REPLICATION In this chapter we consider the fifth step of our generalized replication cycle: genome replication. The genome of the infecting virus is replicated so…
Attachment and Entry of Viruses into Cells
5.1 OVERVIEW OF VIRUS REPLICATION The aim of a virus is to replicate itself, and in order to achieve this aim it needs to enter a host cell, make copies…
Outcomes of Infection for the Host
9.1 INTRODUCTION TO OUTCOMES OF INFECTION FOR THE HOST In the previous few chapters we have looked at aspects of the virus replication cycle that culminate in the exit of…
Virus Vaccines
25.1 INTRODUCTION TO VIRUS VACCINES In this chapter we discuss one of the major applications of virology: the development and use of vaccines against virus diseases in humans and animals….
