Chapter 18 Microfabrication and Microfluidics and Their Application to Clinical Diagnostics Lindsay A.L. Bazydlo, Ph.D. and James P. Landers, Ph.D. Background The first miniaturized analytical device with some degree of…
Chapter 40 Inherited Diseases Cindy L. Vnencak-Jones, Ph.D., F.A.C.M.G. Since the first description of the use of the polymerase chain reaction (PCR) for the diagnosis of sickle cell anemia in…
Chapter 33 The Porphyrias and Other Disorders of Porphyrin Metabolism Michael N. Badminton, M.B., Ch.B, Ph.D., F.R.C.Path., Sharon D. Whatley, Ph.D., Allan C. Deacon, Ph.D., F.R.C.Path. and George H. Elder,…
Chapter 12 Electrophoresis Raymond E. Karcher, Ph.D. and James P. Landers, Ph.D.* Developments in deoxyribonucleic acid (DNA) testing, improvements in ease of performance through automation, and advantages of speed and…
Chapter 24 Tumor Markers Lori J. Sokoll, Ph.D., F.A.C.B., Alex J. Rai, Ph.D., D.A.B.C.C., F.A.C.B. and Daniel W. Chan, Ph.D., D.A.B.C.C., F.A.C.B A tumor marker is a substance produced by…
Chapter 6 Preanalytical Variables and Biological Variation Donald S. Young, M.B., Ph.D. The human body is composed of many different compounds and elements; the concentration or activity of these analytes…
Chapter 20 Point-of-Care Testing Christopher P. Price, Ph.D., F.R.S.C., F.R.C.Path. and Andrew St. John, Ph.D., M.A.A.C.B. Advances in a range of analytical and fabrication technologies, such as (1) thin film…
Chapter 37 Principles of Molecular Biology Rossa W.K. Chiu, M.B.B.S., Ph.D., F.H.K.A.M.(Pathology), F.R.C.P.A. and Y.M. Dennis Lo, M.A., D.M., D.Phil., F.R.C.P.,(Lond. & Edin.), F.R.C.Path., F.R.S. Molecular diagnostics represents one of…
Chapter 42 Molecular Methods in Diagnosis and Monitoring of Infectious Diseases Aaron D. Bossler, M.D., Ph.D. and Angela M. Caliendo, M.D., Ph.D. In the short time since their introduction, nucleic…
