Chapter 57 Pregnancy and Its Disorders Edward R. Ashwood, M.D., David G. Grenache, Ph.D., M.T.(A.S.C.P.), D.A.B.C.C., F.A.C.B. and Geralyn Lambert-Messerlian, Ph.D.* The clinical laboratory has an important role in managing…
Chapter 14 Mass Spectrometry Alan L. Rockwood, Ph.D., D.A.B.C.C., Thomas M. Annesley, Ph.D. and Nicholas E. Sherman, Ph.D.* Mass spectrometry (MS) is a powerful qualitative and quantitative analytical technique that…
Chapter 16 Principles of Immunochemical Techniques Larry J. Kricka, D. Phil., F.A.C.B., C. Chem., F.R.S.C., F.R.C.Path. and Jason Y. Park, M.D., Ph.D., F.A.C.P.* Immunochemical reactions form the basis of a…
Chapter 5 Establishment and Use of Reference Values Gary L. Horowitz, M.D.* Medicine is an art and a science in the service of fellow human beings. To improve the health…
Chapter 44 Hematopoietic Malignancies Kojo S.J. Elenitoba-Johnson, M.D. The hematologic malignancies include leukemias, lymphomas, myeloproliferative disorders, and plasma cell neoplasia. The leukemias are primarily bone marrow and peripheral blood–based processes,…
Chapter 21 Amino Acids, Peptides, and Proteins Glen L. Hortin, M.D., Ph.D* Amino acids, peptides, and proteins are crucial for virtually all biological processes. Amino acids have diverse roles in…
Chapter 53 Pituitary Function and Pathophysiology William E. Winter, M.D., Ishwarlal Jialal, M.D., Ph.D., F.R.C.Path(London), D.A.B.C.C., Mary Lee Vance, M.D. and Roger L. Bertholf, Ph.D.* The pituitary gland (also called…
Chapter 43 Pharmacogenetics Gwendolyn A. McMillin, Ph.D., D.A.B.C.C.(C.C., T.C.)* The term pharmacogenetics comes from merging the names of pharmacology (the study of drugs, particularly drug handling and drug response) and…
Chapter 46 Diabetes Mellitus David B. Sacks, M.B., Ch.B., F.R.C.Path. Diabetes mellitus is a group of metabolic disorders of carbohydrate metabolism in which glucose is underused, producing hyperglycemia. Some patients…
Chapter 56 Reproductive Endocrinology and Related Disorders T. Scott Isbell, Ph.D., Emily Jungheim, M.D. and Ann M. Gronowski, Ph.D.* Reproductive endocrinology encompasses the hormones of the hypothalamic-pituitary-gonadal axis, as well…
