Caliciviridae: The Noroviruses
Caliciviridae: The Noroviruses Kim Y. Green The family Caliciviridae is composed of small (27 to 40 nm), nonenveloped, icosahedral viruses that possess a linear, positive-sense, single-stranded RNA (ssRNA) genome. The…
Hepatitis A Virus
Hepatitis A Virus F. Blaine Hollinger Annette Martin History Reports of icteric disease in ancient Chinese literature, as reviewed by Zuckerman,419 and a letter from Pope Zacharias to Archbishop St….
Rhinoviruses
Rhinoviruses James E. Gern Ann C. Palmenberg History The common cold has been recognized for millennia, and both the illness and prescribed remedies have been influenced by and engendered a…
Enteroviruses: Polioviruses, Coxsackieviruses, Echoviruses, and Newer Enteroviruses
Enteroviruses: Polioviruses, Coxsackieviruses, Echoviruses, and Newer Enteroviruses Mark A. Pallansch M. Steven Oberste J. Lindsay Whitton History The history of enteroviruses (EVs) is very much the history of poliovirus (PV)….
Picornaviridae: The Viruses and their Replication
Picornaviridae: The Viruses and their Replication Vincent R. Racaniello Viruses in the family Picornaviridae have nonenveloped particles with a single-stranded RNA (ssRNA) genome of positive polarity. Among its many members…
Diagnostic Virology
Diagnostic Virology Gregory A. Storch David Wang Diagnostic virology continues to evolve rapidly. Viral testing is now essential for the care of a number of patient groups, including hospitalized patients…
Immunization Against Viral Diseases
Immunization Against Viral Diseases Barney S. Graham James E. Crowe Jr. Julie E. Ledgerwood Both innate and adaptive immune responses mediate host resistance to virus infection. Elements of the innate…
Antiviral Agents
Antiviral Agents Donald M. Coen Douglas D. Richman Overview Medical Importance of Antiviral Drugs and Barriers to Their Development Viruses are a leading cause of disease and death worldwide. Although…
Epidemiology
Epidemiology Neal Nathanson William J. Moss Basic Definitions and Methods Epidemiology deals with the occurrence of diseases in populations. Historically, epidemics of viral disease were recognized long before their causal…
Virus Evolution
Virus Evolution Edward C. Holmes Although Charles Darwin preempted many of the great questions in evolutionary biology, he wrote little about viral infections. Of course, viruses were not formally identified…
