Protocol for the Examination of Gist Specimens Gastrointestinal Stromal Tumor (GIST): Biopsy Surgical Pathology Cancer Case Summary (Checklist) Procedure ____Core needle biopsy ____Endoscopic biopsy ____Other (specify):_____________________________ _____Not specified *Specimen Size…
Antibody Index Antibodies Discussed Antibody Name/Symbol Antibody Description Clones/Alternative Names 34βE12 cytokeratin, high molecular weight (34βE12-; CK1, 5, 10, 14) MA-903, CK903, high molecular weight keratin α1-antichymotrypsin alpha 1 antichromotripsin…
Endometrial Stromal Sarcoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Malignant tumor composed of cells that resemble those of proliferative endometrium Clinical Issues Peak incidence in 4th-5th decades Can…
Interdigitating Reticulum Cell Sarcoma Wesley O. Greaves, MD L. Jeffrey Medeiros, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Clinical Issues Wide age range Single lymph nodes most commonly involved…
Follicular Dendritic Cell Sarcoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Malignant tumor of follicular dendritic cells Clinical Issues Over 1/3 arise in extranodal sites Can metastasize to lymph…
Rosai-Dorfman Disease of Soft Tissue Elizabeth A. Montgomery, MD Key Facts Terminology Lesional histiocytes contain variable numbers of intact lymphocytes within their cytoplasm Phenomenon referred to as lymphophagocytosis or emperipolesis…
Tumoral Calcinosis Julie C. Fanburg-Smith, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Extraskeletal soft tissue calcification with granulomatous response Clinical Issues Most cases < 20 years Some familial…
Granular Histiocytic Reacton Julie C. Fanburg-Smith, MD Aaron Auerbach, MD Key Facts Terminology Post-surgery collections of histiocytes with granular cytoplasm collecting at site of surgical trauma Microscopic Pathology Histiocytes with…
Crystal-Storing Histiocytosis Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Soft tissue aggregate of macrophages containing crystalline material Etiology/Pathogenesis In low-grade B-cell lymphomas Monoclonal gammopathy Myeloma Eosinophilic colitis Treatment of…
Polyvinylpyrrolidone Storage Disease Michael R. Lewin-Smith, MD Julie C. Fanburg-Smith, MD Key Facts Etiology/Pathogenesis PVP storage disease is phagocytic foreign body-type reactive condition Found in aerosol hair sprays, adhesives, lithographic…
