Tumoral Calcinosis



Tumoral Calcinosis


Julie C. Fanburg-Smith, MD

Cyril Fisher, MD, DSc, FRCPath









CT scan of knee in a patient with tumoral calcinosis shows amorphous, dense subcutaneous extraarticular calcification image. The differential diagnosis includes renal osteodystrophy and collagen vascular disease.






Multilocular cystic lesion of tumoral calcinosis demonstrates cysts separated by fibrous septa image. The cysts contain basophilic amorphous material with small foci of granular calcification image.


TERMINOLOGY


Synonyms



  • Lipid calcinosis


  • Calcifying collagenolysis


  • Tumoral lipocalcinosis


Definitions



  • Extraskeletal soft tissue calcification with granulomatous response


ETIOLOGY/PATHOGENESIS


Etiology Theories



  • Inborn error of phosphorus metabolism


Associated Conditions



  • Hyperphosphatemia


Genetics

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Tumoral Calcinosis

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