Basicmedical Key

Hidradenoma Christine J. Ko, MD Key Facts Clinical Issues Solitary dermal nodule Microscopic Pathology May be primarily composed of solid areas, cystic areas, or both Classically does not connect to…

Syringocystadenoma Papilliferum Steven D. Billings, MD Key Facts Clinical Issues Approximately 1/2 present at birth or childhood Scalp most common location, followed by face Often associated with nevus sebaceus (present…

Hidradenoma Papilliferum Senait W. Dyson, MD David Cassarino, MD, PhD Key Facts Terminology Well-circumscribed adenoma with apocrine differentiation Clinical Issues Rare, benign tumor Vulvar or perianal area, predominately in women…

Sebaceous Carcinoma David Cassarino, MD, PhD Key Facts Terminology Adnexal carcinoma that often lacks clear cell features in poorly differentiated cases Etiology/Pathogenesis Strong association with MTS if patients have multiple…

Apocrine Tubular Adenoma Elsa F. Velazquez, MD David Cassarino, MD, PhD Key Facts Clinical Issues Scalp Nodule measuring < 2 cm Microscopic Pathology Intradermal tumor Sometimes arises in association with…

Sebaceoma (Sebaceous Epithelioma) David Cassarino, MD, PhD Key Facts Terminology Sebaceous epithelioma is older term (discouraged) Benign proliferation of mature sebaceous cells with predominant basaloid cell population Etiology/Pathogenesis Some cases…

Sebaceous Hyperplasia Christine J. Ko, MD Key Facts Clinical Issues Commonly on face Yellow to flesh-colored to slightly pink papule Often there is central dell Often biopsied to rule out…

Fibrofolliculoma and Trichodiscoma David Cassarino, MD, PhD Key Facts Terminology Closely related hamartomas with follicular and mesenchymal differentiation Etiology/Pathogenesis Multiple lesions are strongly correlated with Birt-Hogg-Dubé syndrome High risk of…

Pilomatrixoma and Pilomatrical Carcinoma Senait W. Dyson, MD David Cassarino, MD, PhD Key Facts Terminology Calcifying epithelioma of Malherbe Etiology/Pathogenesis Derived from matrix of hair follicle Clinical Issues Pilomatrixoma Relatively…

Tricholemmoma David Cassarino, MD, PhD Key Facts Terminology Tricholemmoma (TL) Benign clear cell adnexal proliferation with external root sheath differentiation Subtype: Desmoplastic tricholemmoma (dTL) Etiology/Pathogenesis Some cases are associated with…