Superficial Cervicovaginal Myofibroblastoma Elizabeth A. Montgomery, MD Key Facts Clinical Issues Adults; mean age about 60 years Polypoid or nodular mass of vagina, cervix, or vulva Treatment: Excision Prognosis: Excellent;…
Cellular Angiofibroma Elizabeth A. Montgomery, MD Key Facts Terminology Synonym: Angiomyofibroblastoma-like tumor of male genital tract Clinical Issues Middle-aged patients More common in women Subcutaneous; usually in vulva or inguinoscrotal…
Angiomyofibroblastoma Marisa Nucci, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Benign stromal tumor composed of numerous capillaries and myofibroblasts Clinical Issues Often thought to represent a cyst Local…
Deep (Aggressive) Angiomyxoma Elizabeth A. Montgomery, MD Key Facts Clinical Issues Deep soft tissues of vulvovaginal region Typically in women in reproductive age group Benign, but recurrences common Macroscopic Features…
Undifferentiated Pleomorphic Sarcoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Anaplastic sarcoma composed of pleomorphic spindle and polygonal cells No other definable differentiation, other than fibroblastic or myofibroblastic Etiology/Pathogenesis…
Undifferentiated Pleomorphic Sarcoma With Prominent Inflammation Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Pleomorphic undifferentiated malignant neoplasm with histiocytic and inflammatory cell infiltrate Microscopic Pathology Sheets of variably atypical…
Fibroepithelial Stromal Polyp Elizabeth A. Montgomery, MD Key Facts Clinical Issues Polypoid lesions presenting in vagina or vulva Possible relationship to hormonal factors Simple excision; occasional recurrences, especially with subsequent…
Undifferentiated Pleomorphic Sarcoma With Giant Cells Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Malignant pleomorphic spindle and polygonal cell sarcoma with osteoclast-type giant cells Tumor morphology shared with several…
Dermatofibrosarcoma Protuberans Thomas Mentzel, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Dermatofibrosarcoma represents superficially located low-grade fibroblastic sarcoma that may show progression to fibrosarcomatous dermatofibrosarcoma protuberans Clinical Issues…
Plexiform Fibrohistiocytic Tumor Julie C. Fanburg-Smith, MD Aaron Auerbach, MD Key Facts Terminology Borderline tumor of fibrohistiocytic phenotype with histiocytic and osteoclast-type giant cells rich; cannonball-like pattern &/or spindled fibroblastic…
