The Nervous System Christopher Dunham, M.D. Arie Perry, M.D. GENERAL NEUROPATHOLOGIC PROCESSES AND PRINCIPLES The practice of neuropathology demands an extensive knowledge of normal central nervous system (CNS) cytology and…

The Eye J. Douglas Cameron, M.D., MBA Raymond G. Areaux Jr., M.D. INTRODUCTION The observations and opinions of surgical pathologists are critical in managing many pediatric ocular conditions including potentially…

Pediatric Forensic Pathology Jonathan Eisenstat, M.D. INTRODUCTION Forensic pathology is the field of medicine that deals with the investigation of death utilizing the scientific method as it pertains to the…

The Placenta Raymond W. Redline, M.D. INTRODUCTION Perinatal pathology, the subdiscipline of pediatric pathology devoted to the study of abnormal pregnancy outcomes, is a dynamic specialty interfacing with obstetrician-gynecologists, neonatologists,…

Transplant Pathology Rish K. Pai, M.D., Ph.D. Anthony Chang, M.D. Aliya N. Husain, M.D. Solid organ transplantation is the optimal mode of therapy for a variety of end-stage diseases, with…

Congenital and Acquired Systemic Infectious Diseases Haresh Mani, M.D. David Parham, M.D. Jennifer Dien Bard, Ph.D., D(ABMM), F.C.C.M. As it takes two to make a quarrel, so it takes two…

Inborn Errors of Metabolism Peter Pytel, M.D. Selene Koo, M.D., Ph.D. Darrel Waggoner, M.D. INTRODUCTION Over 100 years ago, in 1908, Archibald Garrod delivered his four Croonian Lectures during which…

Congenital Anomalies and Malformation Syndromes Joseph R. Siebert, Ph.D. The study of congenital anomalies continues to be hampered by misunderstandings at a number of levels. In many circles, for example,…

First and Second Trimester Pregnancy Loss Jennifer Pogoriler, M.D., Ph.D. Theonia K. Boyd, M.D.* *Based upon the prior edition chapter by Deborah E. McFadden Pathologic examination of the products of…

Chromosomal Abnormalities Robyn C. Reed, M.D., Ph.D. Michelle M. Dolan, M.D. Raj P. Kapur, M.D., Ph.D. Joseph R. Siebert, Ph.D. Advances in genetic testing have blurred the distinction between the…