Chapter 11 Electrochemistry and Chemical Sensors Paul D’Orazio, Ph.D. and Mark E. Meyerhoff, Ph.D.* Electrochemical and optical sensors (and associated biosensors) are firmly established in clinical analysis systems. Sensors for…
Chapter 52 Bone and Mineral Metabolism Juha Risteli, M.D., Ph.D., F.E.B.M.B., William E. Winter, M.D., Michael Kleerekoper, M.D., F.A.C.B., M.A.C.E. and Leila Risteli, M.D., Ph.D., M.A., F.E.B.M.B.* The skeletal system…
Chapter 30 Catecholamines and Serotonin Graeme Eisenhofer, Ph.D., Ronald J. Whitley, Ph.D., D.A.B.C.C. and Thomas G. Rosano, Ph.D., D.A.B.C.C, D.A.B.F.T. Catecholamines and serotonin are biogenic amines that serve as transmitters…
Chapter 48 Kidney Disease Michael P. Delaney, B.Sc., M.D., F.R.C.P., Christopher P. Price, Ph.D., F.R.S.C., F.R.C.Path. and Edmund J. Lamb, Ph.D., F.R.C.Path.* The kidneys play a central role in the…
Chapter 27 Lipids, Lipoproteins, Apolipoproteins, and Other Cardiovascular Risk Factors Alan T. Remaley, M.D., Ph.D., Nader Rifai, Ph.D. and G. Russell Warnick, M.S., M.B.A.* Lipids are ubiquitous in the body…
Chapter 58 Newborn Screening and Inborn Errors of Metabolism Marzia Pasquali, Ph.D., F.A.C.M.G. and Nicola Longo, M.D., Ph.D.* An inborn error of metabolism (IEM) is a genetically determined biochemical disorder…
Chapter 17 Nucleic Acid Techniques Carl T. Wittwer, M.D., Ph.D. and Noriko Kusukawa, Ph.D. Molecular diagnostics requires techniques to detect extremely low concentrations of nucleic acids in a background of…
Chapter 54 The Adrenal Cortex Roger L. Bertholf, Ph.D., Ishwarlal Jialal, M.D., Ph.D., F.R.C.Path(London), D.A.B.C.C. and William E. Winter, M.D.* The adrenal cortex and gonads produce steroid hormones. Steroids are…
Chapter 35 Clinical Toxicology Loralie Langman, Ph.D., F.C.A.C.B., D.A.B.C.C.(C.C.,M.B., T.C.), D.A.B.F.T., Laura Bechtel, Ph.D., D.A.B.C.C. and Christopher P. Holstege, M.D. Toxicology is a broad, multidisciplinary science whose goal is to…
Chapter 59 Hemostasis Russell A. Higgins, M.D., Steve Kitchen, Ph.D. and John D. Olson, M.D., Ph.D. Hemostasis is the mechanism by which animals with a vascular system protect themselves from…
