Autoimmune Polyendocrine Syndromes
Etiology In at least 90% of patients with Cushing’s disease, ACTH excess is caused by a corticotrope pituitary microadenoma, often only a few millimeters in diameter. Pituitary macroadenomas (i.e., tumors >1…
GENERAL & FAMILY MEDICINE
Epidemiology of Cardiovascular Disease
PART 10: Disorders of the Cardiovascular System SECTION 1 INTRODUCTION TO CARDIOVASCULAR DISORDERS 264 Approach to the Patient with Possible Cardiovascular Disease Joseph Loscalzo THE MAGNITUDE OF THE PROBLEM Cardiovascular…
Cutaneous Drug Reactions
(Table 72-9) Disorders of hypopigmentation are often classified as either diffuse or localized. The classic example of diffuse hypopigmentation is oculocutaneous albinism (OCA). The most common forms are due to…
Urinary Tract Infections, Pyelonephritis, and Prostatitis
The mainstay of treatment is adequate rehydration. The treatment of cholera and other dehydrating diarrheal diseases was revolutionized by the promotion of oral rehydration solution (ORS), the efficacy of which…
Lyme Borreliosis
More than 150 species of NTM have been identified. Only a minority of these environmental organisms, which are found in soil and water, are important human pathogens. NTM cause extensive…
The Vasculitis Syndromes
384 The Spondyloarthritides Joel D. Taurog, John D. Carter The spondyloarthritides are a group of overlapping disorders that share certain clinical features and genetic associations. These disorders include ankylosing spondylitis…
Measles (Rubeola)
PREVENTION AND ERADICATION OF POLIOVIRUS (See also Chap. 148) After a peak of 57,879 cases of poliomyelitis in the United States in 1952, the introduction of IPV in 1955 and…
Heritable Disorders of Connective Tissue
PHP-IA AND PHP-IB Individuals with PHP-I, the most common of the disorders, show a deficient urinary cAMP response to administration of exogenous PTH. Patients with PHP-I are divided into type Ia…
Human Papillomavirus Infections
I. Mucocutaneous HSV infections A. Infections in immunosuppressed patients 1. Acute symptomatic first or recurrent episodes: IV acyclovir (5 mg/kg q8h) or oral acyclovir (400 mg qid), famciclovir (500 mg…
Relapsing Fever
More than 150 species of NTM have been identified. Only a minority of these environmental organisms, which are found in soil and water, are important human pathogens. NTM cause extensive…
