Basicmedical Key

Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma Thomas Mentzel, MD Key Facts Terminology Intermediate (locally aggressive, nonmetastasizing) lipogenic neoplasm composed of atypical adipocytes Clinical Issues Accounts for 40-45% of all liposarcomas Occurs most…

Chondroid Lipoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Uncommon benign neoplasm with features of embryonal fat and embryonal cartilage Balanced translocation t(11;16)(q13; p12-13) in 2 cases, thought to…

Lipoblastoma and Lipoblastomatosis Amitabh Srivastava, MD Key Facts Terminology Benign tumor resembling fetal adipose tissue Lipoblastomas are well circumscribed Lipoblastomatosis is deeply infiltrative Clinical Issues Presents in infancy and early…

Spindle Cell/Pleomorphic Lipoma Amitabh Srivastava, MD Key Facts Terminology Benign adipocytic tumor with variable admixture of spindle cells, ropey collagen, and multinucleate tumor giant cells Clinical Issues Typically in older…

Hibernoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Benign tumor with differentiation toward brown fat, most frequently seen in younger adults Clinical Issues Peak incidence in 3rd decade Most…

Myelolipoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Tumor-like lesion resembling bone marrow composed of hemopoietic tissues, fat, and sometimes bone Most cases involve adrenal gland Rarely other sites…

Angiolipoma Amitabh Srivastava, MD Key Facts Terminology Biphasic tumor consisting of mature adipocytes and thin-walled blood vessels with fibrin thrombi Clinical Issues Common in young adults; male predominance Painful tender…

Myolipoma Jonathan B. McHugh, MD Key Facts Terminology Soft tissue neoplasm composed of mature adipose tissue and smooth muscle Clinical Issues Adults; peak in 5th-6th decade Female predilection Most occur…

Lipomatosis Amitabh Srivastava, MD Key Facts Terminology Diffuse overgrowth of mature adipose tissue Clinical Issues Presents as painless mass or with obstructive symptoms Tendency for recurrence due to poor circumscription…

Lipoma Amitabh Srivastava, MD Key Facts Terminology Benign tumor of mature white adipocytes Clinical Issues Surgical excision is curative Higher recurrence rate in intramuscular lipoma Macroscopic Features Most common between…