Myelolipoma



Myelolipoma


Cyril Fisher, MD, DSc, FRCPath









Hematoxylin & eosin shows scanning magnification appearance of myelolipoma. Adrenal glandular tissue is stretched around a circumscribed, nonencapsulated lesion that displays fatty and cellular areas.






CT shows a predominantly fatty mass image replacing and expanding the left adrenal gland. The left kidney image is displaced. These imaging appearances are characteristic of an adrenal myelolipoma.


TERMINOLOGY


Definitions



  • Tumor-like lesion resembling bone marrow composed of hemopoietic tissues, fat, and sometimes bone


  • Mostly in adrenal gland


  • Rarely other sites


ETIOLOGY/PATHOGENESIS


Associated Conditions



  • Cortical adenoma, pheochromocytoma


  • Adrenal cortical hyperplasia



    • Possible effect on hemopoietic stem cell rests


  • Most are idiopathic


CLINICAL ISSUES


Epidemiology



  • Incidence



    • Rare


  • Age



    • Older adults, usually after 4th decade


  • Gender



    • M = F

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Myelolipoma
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