Plasmablastic Lymphoma Arising in HHV8+ Multicentric Castleman Disease L Jeffrey Medeiros, MD Key Facts Terminology PBL-MCD is a monoclonal proliferation of HHV8(+) plasmablasts that express IgMλ and arise in MCD…
Protocol for Examination of Non-Hodgkin Lymphoma Specimens L. Jeffrey Medeiros, MD Non-Hodgkin Lymphoma/Lymphoid Neoplasms: Biopsy, Resection Surgical Pathology Cancer Case Summary (Checklist) Specimen (select all that apply) ____ Lymph node(s)…
ALK+ Diffuse Large B-cell Lymphoma Tariq Muzzafar, MBBS Key Facts Etiology/Pathogenesis ALK gene abnormalities at chromosome 2p23 appear to be key transforming event Result in formation of fusion genes and…
Diffuse Large B-cell Lymphoma, NOS, Centroblastic Francisco Vega, MD, PhD Key Facts Terminology Diffuse proliferation of large neoplastic B cells composed predominantly of centroblasts Typical: Medium to large cells (10-14…
T-cell/Histiocyte-rich Large B-cell Lymphoma Francisco Vega, MD, PhD Key Facts Terminology Large B-cell lymphoma characterized by scattered large lymphoma cells representing < 10% of total cell population Clinical Issues Young…
Diffuse Large B-cell Lymphoma Associated with Chronic Inflammation Wei Liu, MD, PhD L. Jeffrey Medeiros, MD Key Facts Terminology DLBCL-CI is large B-cell neoplasm that occurs in context of longstanding…
Lymphocyte-depleted Hodgkin Lymphoma C. Cameron Yin, MD, PhD Key Facts Clinical Issues < 1% of cases of CHL Lymph nodes: Retroperitoneal or abdominal > peripheral Abdominal organs, bone marrow B…
Burkitt Lymphoma Carlos E. Bueso-Ramos, MD, PhD Key Facts Clinical Issues Median age in adult group is 30 years In the West, BL presents as abdominal mass BL may also…
EBV+ Diffuse Large B-cell Lymphoma of the Elderly Tarlq Muzzzafar, MBBS Key Facts Terminology DLBCL infected by EBV occurring in patients > 50 years old without history of immunodeficiency or…
Lymphadenopathy Secondary to Drug-induced Hypersensitivity Syndrome Tariq Muzzafar, MBBS Key Facts Terminology DIHS is idiosyncratic host reaction to drug involving T-cell/macrophage activation and cytokine release Criteria for diagnosis of DIHS…
