Antibody and Molecular Factor Index Antibodies Discussed Antibody Name/Symbol Antibody Description Clones/Alternative Names Chapters β-catenin beta catenin; involved in regulation of cell adhesion and in signal transduction through Wnt pathway…
Candidiasis Irina Margaritescu, MD, DipRCPath Bruce R. Smoller, MD Key Facts Terminology Common superficial infection of skin and mucous membranes caused by yeasts of genus Candida Etiology/Pathogenesis C. albicans is…
Zygomycosis Brian J. Hall, MD John C. Hall, MD David J. DiCaudo, MD Key Facts Terminology Deep fungal infection caused by 2 orders (Mucorales, Entomophthorales) Microscopic Pathology Mucormycosis Rarely septate,…
Blastomycosis Brian J. Hall, MD David J. DiCaudo, MD Key Facts Etiology/Pathogenesis Exposure to thermally dimorphic fungus Blastomyces dermatitidis found naturally in soil Clinical Issues 2 classic cutaneous presentations Verrucous:…
Histoplasmosis Cornelia S. L. Mller, MD Bruce R. Smoller, MD Key Facts Terminology Systemic fungal infection caused by yeast Histoplasma capsulatum var. capsulatum Clinical Issues Widely distributed with endemic occurrence…
Molluscum Contagiosum Talley Whang, MD Chad Jessup, MD, MS Martin C. Mihm, Jr., MD Key Facts Etiology/Pathogenesis Caused by molluscum contagiosum viruses (poxvirus), transmitted by skin-to-skin contact Clinical Issues Primarily…
Dermatophytosis Christine J. Ko, MD Key Facts Terminology Superficial fungal infection secondary to dermatophytes Dermatophytes belong to 3 genera Trichophyton, Epidermophyton, Microsporum Clinical Issues Classic lesion Annular plaque of erythema…
Herpesvirus Wang L. Cheung, MD, PhD Key Facts Terminology Infection by herpes virus (HSV1, HSV2, and VZV) Clinical Issues Clear fluid-filled vesicles that heal well, usually on mucosa sites (lip,…
Secondary Syphilis Gonzalo De Toro, MD Key Facts Terminology SS occurs 4-8 weeks after primary chancre, usually as maculopapular, scaly patches or plaques characteristically involving palms and soles, extremities, trunk,…
