Basicmedical Key

Juvenile and Adult-type Xanthogranuloma Elizabeth A. Montgomery, MD Key Facts Terminology Stable or regressing histiocytic lesion that usually occurs in childhood Form of non-Langerhans histiocytosis Clinical Issues Majority in individuals…

Osteoma Cutis David Cassarino, MD, PhD Key Facts Etiology/Pathogenesis Primary: May be part of Albright hereditary osteodystrophy or other genetic syndromes Secondary: Associated with preexisting lesions, such as nevi, tumors,…

Chondroma David R. Lucas, MD Key Facts Terminology Benign hyaline cartilage neoplasm of soft tissue with predilection for hands and feet Synonyms: Extraskeletal chondroma, chondroma of soft parts, osteochondroma, myxochondroma…

Atypical Lipomatous Tumor and Liposarcoma Elizabeth A. Montgomery, MD Key Facts Terminology Intermediate (locally aggressive, nonmetastasizing) lipogenic neoplasm composed of atypical adipocytes Clinical Issues Accounts for 40-45% of all liposarcomas…

Hibernoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Benign tumor with differentiation toward brown fat, most frequently seen in younger adults Clinical Issues Peak incidence in 3rd decade Most…

Nevus Lipomatosus Steven D. Billings, MD Key Facts Terminology Connective tissue nevus characterized by mature adipose tissue in reticular dermis Clinical Issues Solitary or multiple grouped papules or polypoid lesions…

Spindle Cell and Pleomorphic Lipoma Amitabh Srivastava, MD Key Facts Terminology Benign adipocytic tumors with variable admixture of spindle cells, mucinous stroma, ropey collagen, and multinucleate giant cells Clinical Issues…

Chondroid Lipoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Uncommon benign neoplasm with features of embryonal fat and embryonal cartilage Balanced translocation t(11;16)(q13; p12-13) in some cases; thought to…

Angiolipoma Amitabh Sricatava, MD Key Facts Terminology Biphasic tumor consisting of mature adipocytes and thin-walled blood vessels with fibrinoid thrombi Clinical Issues Common in young adults; male predominance Painful tender…

Lipoma Amitabh Srivastava, MD Key Facts Terminology Benign tumor of mature white adipocytes Clinical Issues Surgical excision is curative Higher recurrence rate in intramuscular lipoma Macroscopic Features Most common between…