Juvenile and Adult-type Xanthogranuloma

Juvenile and Adult-type Xanthogranuloma

Elizabeth A. Montgomery, MD

This is a typical appearance of a juvenile xanthogranuloma removed from the face of a small boy. The lesion is uniform and cellular and proliferates in the dermis with no grenz zone.

Many Touton giant cells image can be seen in this juvenile xanthogranuloma. The background cells are spindled to ovoid with eosinophilic cytoplasm, which shows only minimal lipid in this case.



  • Juvenile xanthogranuloma (JXG)


  • Nevoxanthoendothelioma


  • Stable or regressing histiocytic lesion that usually occurs in childhood

    • Form of non-Langerhans histiocytosis



  • Incidence

    • Rare

  • Age

    • Majority in individuals under 3 years

      • Visceral examples almost exclusively in infants and children

    • 13-30% in older children and adults

  • Gender

    • Slight male predominance

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Juvenile and Adult-type Xanthogranuloma
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