Chondroid Lipoma



Chondroid Lipoma


Khin Thway, BSc, MBBS, FRCPath










Gross photograph of chondroid lipoma shows a circumscribed lesion with a multilobulated, yellow to tan cut surface and prominent hemorrhage.






Chondroid lipoma shows islands of rounded cells in a hypocellular chondroid-like stroma. The cells are lipoblastic-like, with multivacuolated, lipid-containing cytoplasm image. Mature adipocytes are present.


TERMINOLOGY


Definitions



  • Uncommon benign neoplasm with features of embryonal fat and embryonal cartilage



    • Most frequently affects proximal limbs and limb girdles of adult women


  • Often mistaken for sarcomas


ETIOLOGY/PATHOGENESIS


Developmental Anomaly



  • Etiology unknown


CLINICAL ISSUES


Epidemiology



  • Age



    • Adults, peak incidence in 3rd and 4th decades


  • Gender



    • M:F = 1:4


Site



  • Predominantly proximal limbs and limb girdles


  • Trunk, head and neck (especially oral cavity)


  • Both superficial (subcutaneous) and deep locations


Presentation



  • Painless mass



    • Recent enlargement in 1/2 of cases

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Chondroid Lipoma
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