Hepatitis C Virus

Jul 7, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Hepatitis C Virus

Hepatitis C Virus Anthony Chang, MD Key Facts Terminology Hepatitis C virus (HCV) Wide spectrum of immune complex-mediated glomerular injuries in association with HCV infection Clinical Issues Over 200 million…

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Obstructive Nephropathy

Jul 7, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Obstructive Nephropathy

Obstructive Nephropathy Sanjay Jain, MD, PhD Helen Liapis, MD Key Facts Terminology Acute or chronic damage to kidney due to obstruction of urine flow Etiology/Pathogenesis Many causes, congenital and acquired…

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Nephrolithiasis

Jul 7, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Nephrolithiasis

Nephrolithiasis Shane M. Meehan, MBBCh Key Facts Terminology Concretion of urinary mineral or inorganic crystals in kidney Etiology/Pathogenesis Causes 25% known cause 50% idiopathic hypercalciuria 25% unknown cause Clinical Issues…

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Reflux Nephropathy

Jul 7, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Reflux Nephropathy

Reflux Nephropathy Sanjay Jain, MD, PhD Helen Liapis, MD Key Facts Terminology Reflux nephropathy: Renal parenchymal scarring due to urine reflux Etiology/Pathogenesis Vesicoureteral reflux (VUR), UTIs Exposure of kidneys to…

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Amyloidosis

Jul 7, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Amyloidosis

Amyloidosis A. Brad Farris, III, MD Key Facts Terminology Accumulation of any 1 of > 20 amyloid proteins, characterized by apple-green birefringence after Congo red stain due to β-pleated sheet…

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Collapsing Glomerulopathy

Jul 7, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Collapsing Glomerulopathy

Collapsing Glomerulopathy A. Brad Farris, III, MD Key Facts Etiology/Pathogenesis Podocyte proliferation and dedifferentiation are thought to play a role Idiopathic most common form Heterogeneous secondary forms Infection: HIV, parvovirus…

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Renal Artery Stenosis

Jul 7, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Renal Artery Stenosis

Renal Artery Stenosis A. Brad Farris, III, MD Key Facts Etiology/Pathogenesis Renal artery stenosis from variety of potential causes results in ischemic atrophy Atherosclerosis with atheromatous plaques is one of…

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Drug-induced Acute Interstitial Nephritis

Jul 7, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Drug-induced Acute Interstitial Nephritis

Drug-induced Acute Interstitial Nephritis Neeraja Kambham, MD Key Facts Terminology Acute tubulointerstitial inflammation due to allergic reaction to a drug Etiology/Pathogenesis T-cell-mediated hypersensitivity reaction Idiosyncratic reaction, not dose dependent Clinical…

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