Principles of Clinical Chemistry Automation

Mar 9, 2017 by in BIOCHEMISTRY Comments Off on Principles of Clinical Chemistry Automation

FIGURE 7.1 Modular chemistry/immunoassay analyzers. (A) Siemens Dimension Vista 500. (Photograph courtesy of Siemens.) (B) Roche MODULAR ANALYTICS. (Photograph courtesy of Roche Diagnostics.) (C) Abbott ARCHITECT ci8200. (Photograph courtesy of…

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Trace and Toxic Elements

Mar 9, 2017 by in BIOCHEMISTRY Comments Off on Trace and Toxic Elements

at http://thepoint.lww.com OVERVIEW AND OBJECTIVES Almost half of the elements listed in the periodic table have been found in the human body.1 An element is considered essential if a deficiency…

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Clinical Chemistry and the Geriatric Patient

Mar 9, 2017 by in BIOCHEMISTRY Comments Off on Clinical Chemistry and the Geriatric Patient

at http://thepoint.lww.com The number and proportion of older individuals in the total population is increasing rapidly in the United States and other developed nations. There are a number of physiological…

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Porphyrins and Hemoglobin

Mar 9, 2017 by in BIOCHEMISTRY Comments Off on Porphyrins and Hemoglobin

at http://thepoint.lww.com Hemoglobin and myoglobin are chemically similar molecules that contain porphyrin groups. Porphyrins are cyclic structures comprised of four pyrrole rings joined by methine bridges. The arrangement of the…

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Toxicology

Mar 9, 2017 by in BIOCHEMISTRY Comments Off on Toxicology

at http://thepoint.lww.com Key Terms Bioaccumulation Body burden Dose–response relationship Drugs of abuse ED50 Individual dose–response relationship LD50 Poisons Quantal dose–response relationship TD50 Therapeutic index Toxicokinetics Toxicology Toxins Xenobiotics Toxicology is…

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Calcium Homeostasis and Hormonal Regulation

Mar 9, 2017 by in BIOCHEMISTRY Comments Off on Calcium Homeostasis and Hormonal Regulation

at http://thepoint.lww.com CALCIUM HOMEOSTASIS Serum calcium level is maintained at a constant level for the optimal excitability of neural and muscular tissue and the coordinated functioning of various organ systems…

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Molecular Theory and Techniques

Mar 9, 2017 by in BIOCHEMISTRY Comments Off on Molecular Theory and Techniques

FIGURE 9.1 DNA molecule. The double helix of the DNA is shown along with details of how the bases, sugars, and phosphates connect to form the structure of the molecule….

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Gonadal Function

Mar 9, 2017 by in BIOCHEMISTRY Comments Off on Gonadal Function

at http://thepoint.lww.com THE TESTES By the 6th week of development in both sexes, the primordial germ cells have migrated from their extraembryonic location to the gonadal ridges, where they are…

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Pancreatic Function and Gastrointestinal Function

Mar 9, 2017 by in BIOCHEMISTRY Comments Off on Pancreatic Function and Gastrointestinal Function

at http://thepoint.lww.com The gastrointestinal (GI) system is composed of the mouth, esophagus, stomach, small intestine, and large intestine. Digestion, which is primarily a function of the small intestine, is the…

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The Thyroid Gland

Mar 9, 2017 by in BIOCHEMISTRY Comments Off on The Thyroid Gland

at http://thepoint.lww.com THE THYROID The thyroid gland is responsible for the production of two hormones: thyroid hormone and calcitonin. Calcitonin is secreted by parafollicular C cells and is involved in…

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