CHAPTER 23 Essential thrombocythemia and primary myelofibrosis HM. Kvasnicka Chapter contents INTRODUCTION 347 ESSENTIAL THROMBOCYTHEMIA (ET) 348 Clinical features 349 Molecular data 349 Blood and bone marrow findings 349 PRIMARY…
CHAPTER 20 Myelodysplastic syndromes BS. Wilkins, A. Porwit Chapter Contents DEFINITION 303 EPIDEMIOLOGY 303 CLASSIFICATION 304 DIAGNOSIS 304 BLOOD-FILM EXAMINATION 306 Erythrocytes 306 Leukocytes 307 Platelets 308 BONE MARROW EXAMINATION…
CHAPTER 28 The chronic lymphoid leukemias R. Rosenquist, A. Porwit Chapter contents CHRONIC LYMPHOCYTIC LEUKEMIA 407 Clinical features 407 Pathologic features 408 Peripheral blood 408 Bone marrow 408 Other tissues…
CHAPTER 18 Acute myeloid leukemias SD. Boyd, DA. Arber Chapter Contents INTRODUCTION 273 CLASSIFICATION SYSTEMS 274 Methods for diagnosis and classification 274 Clinical history 274 Peripheral blood and bone marrow…
CHAPTER 1 Normal blood cells SN. Wickramasinghe, WN. Erber Chapter contents ERYTHROCYTES 3 Morphology 3 Red cell parameters 3 Red cell life span 4 Functions of red cells 5 Reticulocytes…
CHAPTER 25 Myeloproliferative neoplasms with eosinophilia BJ. Bain Chapter contents MYELOID AND LYMPHOID NEOPLASMS WITH PDGFRA REARRANGEMENT 371 Clinical features 372 Pathologic features 372 Peripheral blood 372 Bone marrow 373…
CHAPTER 8 Erythroenzyme disorders DM. Layton, DR. Roper Chapter contents INTRODUCTION 121 CLINICAL FEATURES 121 BLOOD CELL MORPHOLOGY 122 BIOCHEMICAL INVESTIGATION OF ERYTHROENZYME DISORDERS 126 MOLECULAR BASIS OF ERYTHROENZYME DISORDERS…
CHAPTER 22 Erythrocytosis and polycythemia J D. van der Walt Chapter contents INTRODUCTION 333 THE PATHOLOGY OF ERYTHROCYTOSIS 334 CONGENITAL ERYTHROCYTOSIS 334 Associated with reduced P50 334 High-oxygen-affinity hemoglobinopathy 334…
CHAPTER 19 Acute lymphoblastic leukemia/lymphoma and mixed phenotype acute leukemias A. Porwit, M-C. Béné Chapter Contents INTRODUCTION 289 ACUTE LYMPHOBLASTIC LEUKEMIA/LYMPHOMA 289 Clinical presentation 289 Classification 290 Cytology, cytochemistry and…
CHAPTER 11 Iron deficiency anemia, anemia of chronic disorders and iron overload MJ. Pippard Chapter contents INTRODUCTION 173 Spectrum of pathology related to disorders of iron metabolism 174 Iron deficiency…
