Atypical Nevus of the Genital Tract
Atypical Nevus of the Genital Tract Russell Ball, MD Marisa R. Nucci, MD Key Facts Terminology Benign melanocytic proliferation with architectural and cytologic features that differ from common nevi and…
PATHOLOGY & LABORATORY MEDICINE
Malignant Melanoma, Vulva
Malignant Melanoma, Vulva Maria Angelica Selim, MD Key Facts Clinical Issues Predominantly postmenopausal Mass, bleeding, discharge, pruritus, pain ˜ 30% amelanotic, especially mucosal surfaces Macroscopic Features Macule or plaque with…
Squamous Cell Carcinoma, General Concepts
Squamous Cell Carcinoma, General Concepts Antonio L. Cubilla, MD Alcides Chaux, MD Elsa F. Velazquez, MD Distal penis includes the glans (mostly composed of corpus spongiosum and containing the penile…
Extramammary Paget Disease
Extramammary Paget Disease Maria Angelica Selim, MD Russell Ball, MD Key Facts Terminology Intraepidermal adenocarcinoma (primary or secondary) with frequent extension into adnexal structures; rarely invasive Clinical Issues Often, clinically…
Fibroepithelial Stromal Polyp
Fibroepithelial Stromal Polyp Marisa R. Nucci, MD Key Facts Clinical Issues More common during pregnancy Vulva, vagina, and rarely cervix Local excision Macroscopic Features Usually < 5 cm Typically polypoid…
Squamous Hyperplasia
Squamous Hyperplasia Antonio L. Cubilla, MD Alcides Chaux, MD Elsa F. Velazquez, MD Key Facts Terminology Thickening of mucosal squamous epithelium without atypia Most common epithelial alteration associated with penile…
Mixed Carcinoma
Mixed Carcinoma Antonio L. Cubilla, MD Alcides Chaux, MD Elsa F. Velazquez, MD Key Facts Terminology 20% or more of at least 1 of the histological components Macroscopic Features Glans…
HPV-associated Lesions
HPV-associated Lesions Antonio L. Cubilla, MD Alcides Chaux, MD Elsa F. Velazquez, MD Key Facts Terminology Synonyms include condyloma acuminatum and giant condyloma Exophytic and verruciform nonmalignant epithelial tumors Clear…
Mixed Germ Cell Tumors
Mixed Germ Cell Tumors Steven S. Shen, MD, PhD Jae Y. Ro, MD, PhD Key Facts Terminology Germ cell tumor composed of > 1 histologic type of germ cell tumor,…
Squamous Cell Carcinoma, Usual Type
Squamous Cell Carcinoma, Usual Type Antonio L. Cubilla, MD Alcides Chaux, MD Elsa F. Velazquez, MD Key Facts Etiology/Pathogenesis HPV infection in about 1/4 of cases Macroscopic Features Glans frequently…
