Atypical Nevus of the Genital Tract



Atypical Nevus of the Genital Tract


Russell Ball, MD

Marisa R. Nucci, MD










Florid nests of melanocytes are present at the dermal-epidermal junction showing prominent retraction artifact in atypical nevus of the genital tract. Notice the melanocytic maturation in the dermis image.






Unusually large melanocytic nests image are a characteristic feature of atypical nevus of the genital tract. The melanocytes show uniform cytologic atypia.


TERMINOLOGY



Synonyms



  • Melanocytic nevus with site-specific changes


  • Nevus of special site


  • Atypical compound nevus, genital type


  • Nevus with site-related atypia



ETIOLOGY/PATHOGENESIS


Unknown



  • BRAF V600E mutation may occur




MACROSCOPIC FEATURES


General Features



  • Pink, tan, brown, or black macule or papule


  • Usually well demarcated


  • Pigment typically evenly distributed within lesion


Size



  • Range: 2-20 mm (mean: 6 mm, median: 5 mm)


Jul 7, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Atypical Nevus of the Genital Tract

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