Gallbladder Carcinoma Cancer Protocol Laura Webb Lamps, MD Gallbladder: Resection/Cholecystectomy Surgical Pathology Cancer Case Summary (Checklist) Specimen (select all that apply) ___Gallbladder ___Liver ___Extrahepatic bile duct ___Other (specify):____________________ ___Not specified…
Cholesterol Polyps and Cholesterolosis Kari D. Caradine, MD Key Facts Terminology Accumulation of neutral lipid within macrophages of lamina propria of gallbladder Macroscopic Features Lipid droplets appear as yellow flecks…
Embryonal Rhabdomyosarcoma Laura Webb Lamps, MD Key Facts Terminology Botryoid rhabdomyosarcoma is most common pediatric neoplasm of extrahepatic biliary tree Macroscopic Features More common in biliary tree than gallbladder Grape-like…
Adenocarcinoma of the Extrahepatic Bile Ducts Hanlin L. Wang, MD, PhD Key Facts Terminology Malignant neoplasm arising from epithelium lining right and left hepatic ducts, common hepatic duct, and common…
Poorly Differentiated Neuroendocrine Carcinoma, Gallbladder Laura Webb Lamps, MD Key Facts Terminology Similar to small cell carcinomas in other organs Clinical Issues Highly aggressive neoplasm Microscopic Pathology Round to spindled…
Carcinoid Tumor Kari D. Caradine, MD Key Facts Clinical Issues Rare primary neoplasm of biliary tract All tumors have metastatic potential Risk is mostly dependent on location in GI tract,…
Squamous/Adenosquamous Carcinoma, Gallbladder Joseph Misdraji, MD Key Facts Terminology Squamous cell carcinoma shows only squamous differentiation whereas adenosquamous carcinoma shows both glandular and squamous differentiation Clinical Issues 1.4-9.6% of gallbladder…
Biliary Papillomatosis Laura Webb Lamps, MD Key Facts Terminology Multiple adenomas of bile ducts Clinical Issues Very rare; some cases associated with familial adenomatous polyposis Resection often not possible given…
Intestinal-type Adenoma Vikram Deshpande, MD Key Facts Terminology Gallbladder polyp composed of intestinal-type epithelium Clinical Issues Progression to carcinoma uncommon Microscopic Pathology Resemble colonic adenomas Tubular, papillary to mixed tubulopapillary…
Pyloric Gland Adenoma Vikram Deshpande, MD Key Facts Terminology Benign neoplasm of glandular epithelium showing pyloric differentiation Clinical Issues Usually discovered incidentally Macroscopic Features Usually solitary sessile lesions Microscopic Pathology…
