Embryonal Rhabdomyosarcoma

Embryonal Rhabdomyosarcoma

Laura Webb Lamps, MD

Closely packed neoplastic cells of rhabdomyosarcoma (RMS) form a dense “cambium layer” beneath a single layer of intact biliary epithelium. Deep to this are spindled tumor cells within a myxoid stroma.

The tumor cells are typically small and hyperchromatic. Some cells have abundant eosinophilic cytoplasm image.



  • Rhabdomyosarcoma (RMS)


  • Primary rhabdomyosarcoma, embryonal type, arising in biliary tree or gallbladder

    • Botryoid rhabdomyosarcoma is most common neoplasm of extrahepatic biliary tree in childhood



  • Age

    • Most frequently described in children, in extrahepatic biliary tree

      • Range: 16 months to 11 years; mean age: 4.5 years

    • Occasionally seen in adults

      • Usually in gallbladder (rather than biliary tree) of elderly patients

  • Gender

    • No gender predilection

Jul 7, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Embryonal Rhabdomyosarcoma
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