Hobnail (Targetoid Hemosiderotic) Hemangioma David Cassarino, MD, PhD Key Facts Terminology Targetoid hemosiderotic hemangioma Benign vascular proliferation, typically wedge-shaped, showing intravascular papillae and hobnailed endothelial cells Etiology/Pathogenesis Postulated to represent…
Epithelioid Sarcoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Malignant mesenchymal tumor resembling carcinoma or granuloma Classical and proximal aggressive forms Etiology/Pathogenesis Some have abnormalities of chromosome 22q Clinical…
Spindle Cell Hemangioma Steven D. Billings, MD Key Facts Terminology Formerly called spindle cell hemangioendothelioma Clinical Issues Subcutaneous mass Usually acral location Sometimes multifocal Local recurrence in 50-60% of cases…
Angiolymphoid Hyperplasia with Eosinophilia Lester D. R. Thompson, MD Key Facts Terminology Benign vascular tumor with well-formed, immature blood vessels associated with prominent inflammatory component, rich in eosinophils Clinical Issues…
Glomeruloid Hemangioma David Cassarino, MD, PhD Key Facts Terminology Glomeruloid angioma Etiology/Pathogenesis Association with polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes (POEMS) or multicentric Castleman syndrome in most cases Clinical Issues…
Tufted Angioma David Cassarino, MD, PhD Key Facts Terminology Acquired tufted angioma (ATA) Angioblastoma (of Nakagawa) Multiple cannonball-like cellular collections of small vessels in dermis Clinical Issues Children and young…
Pseudosarcomatous Fibroblastic Proliferations Elizabeth A. Montgomery, MD Key Facts Terminology Nodular fasciitis: Rapidly growing myofibroblastic proliferation that is often cellular and mitotically active, but behaves in a benign fashion Intravascular…
Arteriovenous Hemangioma (Malformation) Steven D. Billings, MD Key Facts Terminology Acral arteriovenous tumor Cirsoid aneurysm Benign vascular tumor composed of thick- and thin-walled blood vessels Microscopic Pathology Circumscribed tumor in…
Infantile (Juvenile) Hemangioma Jeremy C. Wallentine, MD Key Facts Clinical Issues Most common tumor of infancy Appear within 1st few weeks of life Rapidly enlarge over several months All eventually…
Myxofibrosarcoma David Cassarino, MD, PhD Key Facts Terminology Myxofibrosarcoma represents a spectrum of malignant fibroblastic neoplasms with variably myxoid stroma and characteristic elongated curvilinear vessels Clinical Issues One of most…
