Angiolymphoid Hyperplasia with Eosinophilia

Angiolymphoid Hyperplasia with Eosinophilia

Lester D. R. Thompson, MD

Histology at scanning magnification shows an intact surface epithelium with a richly vascularized stroma containing inflammatory cells.

High magnification shows endothelial hyperplasia with a thickened vessel wall image, and numerous inflammatory cells, including eosinophils image, in the surrounding tissue. Note the extravasated erythrocytes.



  • Angiolymphoid hyperplasia with eosinophilia (ALHE)


  • Epithelioid hemangioma

  • Nodular, angioblastic hyperplasia with eosinophilia and lymphofolliculosis


  • Benign vascular tumor with well-formed, immature blood vessels, most of which are lined by plump, epithelioid (histiocytoid) endothelial cells

  • Most cases have prominent inflammatory component in which eosinophils are conspicuous feature

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Angiolymphoid Hyperplasia with Eosinophilia

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