Nasopharyngeal Angiofibroma Lester Thompson, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Benign, highly cellular, and richly vascularized mesenchymal neoplasm arising in nasopharynx in males Clinical Issues Recurrent, spontaneous…
Giant Cell Angiofibroma Amitabh Srivastava, MD Key Facts Terminology Benign fibroblastic tumor with multinucleated tumor giant cells and angiectoid spaces May be related to solitary fibrous tumor/hemangiopericytoma group Clinical Issues…
Dermatomyofibroma David S. Cassarino, MD, PhD Key Facts Terminology Myofibroblastic tumor with features overlapping with dermatofibroma Clinical Issues Slow-growing plaque or nodule Microscopic Pathology Dermal-based spindle cell proliferation Tumor is…
Fibrous Hamartoma of Infancy Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Benign superficial fibrous lesion occurring during 1st 2 years of life Clinical Issues Congenital in up to 25%…
Ischemic Fasciitis Elizabeth A. Montgomery, MD Key Facts Terminology Pseudosarcomatous proliferation Clinical Issues Mean age: 8th decade Most cases do not recur following excision Microscopic Pathology Most involve deep subcutis…
Nodular Fasciitis Elizabeth A. Montgomery, MD Key Facts Clinical Issues Age: 3rd-4th decades Gender: M = F Most lesions are benign and do not recur, even if incompletely excised Simple…
Proliferative Fasciitis/Myositis Elizabeth A. Montgomery, MD Key Facts Terminology Tumefactive subcutaneous (fasciitis) or intramuscular (myositis) proliferation featuring ganglion-like fibroblasts Macroscopic Features Usually 2-3 cm Microscopic Pathology Mostly plump stellate to…
Desmoplastic Fibroblastoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Rare benign fibrous soft tissue neoplasm occurring mainly in adult males and consisting of paucicellular arrays of stellate and spindle…
Juvenile Hyaline Fibromatosis Elizabeth A. Montgomery, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Related disorder: Infantile systemic hyalinosis (ISH) Clinical Issues Autosomal recessive transmission Infantile presentation of lesions…
Fibromatosis Colli Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Fibrosing lesion of infants involving muscles of head and neck Etiology/Pathogenesis Rarely familial Obstetric trauma has been proposed as causal…
