Proliferative Fasciitis/Myositis

Proliferative Fasciitis/Myositis

Elizabeth A. Montgomery, MD

Hematoxylin & eosin shows proliferative fasciitis at low magnification. It tracks along fibrous septa and is somewhat less cellular in the center image, where there is keloid-like collagen.

Hematoxylin & eosin shows the so-called ganglion-like cells image of proliferative fasciitis. These are fibroblasts, but their macronucleoli are reminiscent of those found in ganglion cells.



  • Tumefactive subcutaneous (fasciitis) or intramuscular (myositis) proliferation featuring ganglion-like fibroblasts

    • Background of myofibroblasts and fibroblasts similar to those in nodular fasciitis



  • Incidence

    • Rare; less common than nodular fasciitis

  • Age

    • Middle-aged and older adults; rare in children

  • Gender

    • No predominance


  • Proliferative fasciitis: Upper extremity (forearm) > lower extremity > trunk

  • Proliferative myositis: Trunk > shoulder girdle > upper arm > thigh


  • Rapidly growing painless mass; more likely to be painful than nodular fasciitis

  • Usually no history of trauma

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Proliferative Fasciitis/Myositis

Full access? Get Clinical Tree

Get Clinical Tree app for offline access
%d bloggers like this: