Proliferative Fasciitis/Myositis



Proliferative Fasciitis/Myositis


Elizabeth A. Montgomery, MD









Hematoxylin & eosin shows proliferative fasciitis at low magnification. It tracks along fibrous septa and is somewhat less cellular in the center image, where there is keloid-like collagen.






Hematoxylin & eosin shows the so-called ganglion-like cells image of proliferative fasciitis. These are fibroblasts, but their macronucleoli are reminiscent of those found in ganglion cells.


TERMINOLOGY


Definitions



  • Tumefactive subcutaneous (fasciitis) or intramuscular (myositis) proliferation featuring ganglion-like fibroblasts



    • Background of myofibroblasts and fibroblasts similar to those in nodular fasciitis


CLINICAL ISSUES


Epidemiology



  • Incidence



    • Rare; less common than nodular fasciitis


  • Age



    • Middle-aged and older adults; rare in children


  • Gender



    • No predominance


Site



  • Proliferative fasciitis: Upper extremity (forearm) > lower extremity > trunk


  • Proliferative myositis: Trunk > shoulder girdle > upper arm > thigh


Presentation



  • Rapidly growing painless mass; more likely to be painful than nodular fasciitis


  • Usually no history of trauma

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Proliferative Fasciitis/Myositis
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