Kaposi Sarcoma Thomas Mentzel, MD Key Facts Terminology Locally aggressive endothelial neoplasm associated with human herpes virus 8 Clinical Issues Most typical site of involvement is skin Mucosal membranes, lymph…

Epithelioid Hemangioendothelioma Thomas Mentzel, MD Key Facts Terminology Vascular neoplasm with metastatic potential composed of epithelioid endothelial cells Clinical Issues Rare vascular tumor Superficial or deep soft tissue Rare in…

Epithelioid Sarcoma-Like Hemangioendothelioma Steven D. Billings, MD Key Facts Terminology Vascular tumor of apparent intermediate malignancy that histologically closely resembles epithelioid sarcoma Clinical Issues Presents most commonly in young adults…

Papillary Intralymphatic Angioendothelioma (Dabska) David S. Cassarino, MD, PhD Julie C. Fanburg-Smith, MD Key Facts Terminology Dabska tumor Endovascular papillary angioendothelioma Clinical Issues Typically occur in children (minority in adults)…

Atypical Vascular Proliferation Thomas Mentzel, MD Key Facts Terminology Vascular proliferation after radiotherapy excluding obvious post-irradiation angiosarcoma, arising predominantly in breast Clinical Issues Exact incidence is difficult to establish Occurs…

Kaposiform Hemangioendothelioma Steven D. Billings, MD Key Facts Clinical Issues Presents in infants and young children Associated with Kasabach-Merritt syndrome (especially retroperitoneal tumors) Consumptive coagulopathy Thrombocytopenia Rare regional lymph node…

Lymphangioma and Lymphangiomatosis David S. Cassarino, MD, PhD Key Facts Terminology Lymphangioma circumscriptum (superficial lymphangioma) (LAC) Lymphangiomatosis (systemic angiomatosis) (LAS) Cystic lymphangioma (cystic hygroma) Deep lymphangioma (cavernous lymphangioma) Etiology/Pathogenesis Most…

Massive Localized Lymphedema in Morbid Obesity Steven D. Billings, MD Key Facts Clinical Issues Seen in morbidly obese patients (> 300 lbs) Macroscopic Features Overlying skin has “peau d’orange” appearance…

Progressive Lymphangioma David S. Cassarino, MD, PhD Key Facts Terminology Benign localized proliferation of lymphatic vessels Clinical Issues Usually presents on lower extremities but may occur anywhere Prognosis excellent; local…

Angiomatosis David R. Lucas, MD Key Facts Terminology Diffuse, benign, vascular lesion of soft tissue affecting large segments of body or multiple tissue planes in contiguous fashion Clinical Issues Most…