Kaposiform Hemangioendothelioma

Kaposiform Hemangioendothelioma

Steven D. Billings, MD

Clinical photograph shows a large inguinal tumor in an infant. More superficial tumors typically present as an erythematous or violaceous mass.

Hematoxylin & eosin shows proliferation of spindled endothelial cells. The spindled cells are arranged in short fascicles and form slit-like vascular lumens similar to Kaposi sarcoma.



  • Age

    • Majority present in childhood to teen years

    • Approximately 1/2 of kaposiform hemangioendothelioma cases present in 1st year of life


  • Painful or painless mass

    • Presents as superficial or deep mass

    • Cutaneous lesions present as violaceous plaques

    • Deep tumors often multiple nodules

    • Associated with Kasabach-Merritt syndrome (especially retroperitoneal tumors)

      • Consumptive coagulopathy

      • Thrombocytopenia

      • Majority of all cases of Kasabach-Merritt syndrome associated with kaposiform hemangioendothelioma

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Kaposiform Hemangioendothelioma
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